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PLRG1 is a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Name: | pleiotropic regulator 1 |
Synonyms: | PLRG1, Cwc1, Pleiotropic regulator 1, PRPF46, PRL1, PRP46, TANGO4 |
Target Sequences: | NM_002669 NP_002660.1 O43660 |
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