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MMP3

matrix metallopeptidase 3 (stromelysin 1, progelatinase)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene Name: matrix metallopeptidase 3 (stromelysin 1, progelatinase)
Family/Subfamily: Protease , Metallopeptidase M10A
Synonyms: MMP3, CHDS6, MMP-3, Prostromelysin-1, Proteoglycanase, SL-1, STR1, Matrix metalloproteinase-3, Transin, Transin-1, SLN-1, STMY, Progelatinase, STMY1, Stromelysin-1
Target Sequences: NM_002422 NP_002413.1 P08254

Publications (1)

1
Matrix metalloproteinases are possible mediators for the development of alimentary tract mucositis in the dark agouti rat. Al-Dasooqi N, Gibson RJ, Bowen JM, Logan RM, Stringer AM, Keefe DM. Experimental biology and medicine (Maywood, N.J.). 2010 235:1244-56. (IHC) [PubMed:20682600]

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Antibodies (194)
ELISA Kits (52)
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MMP3 (267)
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MMP3 Antibody - Anti-MMP3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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MMP3 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
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MMP3 Mouse anti-Human Monoclonal Antibody
Pig, Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$832
MMP3 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$669
MMP3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
2.188 - 140 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
MMP3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
MMP3 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
MMP3 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
MMP3 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using Mmp3 Antibody at dilution of 1:20
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MMP3 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
MMP3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
4.7 - 300 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$889
MMP3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Dog
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$854
MMP3 Protein - Recombinant Matrix Metalloproteinase 3 By SDS-PAGE
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E. coli
His
21.4 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
MMP3 Antibody - Immunohistochemical analysis of MMP3 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MMP3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
MMP3 Antibody - MMP3 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MMP3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Horse, Human
WB
Unconjugated
100 µl/$424
MMP3 Antibody
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MMP3 Rabbit anti-Cow Polyclonal Antibody
Bovine, Cow
WB
Unconjugated
100 µl/$317; 200 µl/$362; 500 µl/$513; 1 ml/$589; 2 ml/$812; 5 ml/$1,324
MMP3 Antibody - 1:100 staining human kidney tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22 °C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MMP3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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MMP3 Mouse anti-Human Monoclonal (C-Terminus) (1B4) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$611
MMP3 Antibody - Left: IHC of human gastric carcinoma tissue using MMP-3 antibody (Matrix Metalloproteinase 3 (MMP3)). Right: Western blot of recombinant human MMP-3 proenzyme using MMP-3 antibody.
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MMP3 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
200 µg/$454
MMP3 ELISA Kit
Select
Sandwich
96-Well Microplate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$745
MMP3 Antibody - Western blot of recombinant human MMP-3 protein using anti-MMP-3, clone F36P1B4.
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MMP3 Mouse anti-Human Monoclonal (F36P1B4) Antibody
Human, Monkey
ELISA, WB
Unconjugated
100 µg/$359
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MMP3 Rabbit anti-Human Polyclonal (aa30-59) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
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MMP3 Rabbit anti-Human Polyclonal (aa30-59) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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MMP3 Rabbit anti-Human Polyclonal (aa30-59) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
Select
MMP3 Rabbit anti-Human Polyclonal (aa30-59) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
Select
MMP3 Rabbit anti-Human Polyclonal (aa30-59) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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MMP3 Rabbit anti-Human Polyclonal (aa30-59) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
Viewing 1-25 of 267 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).