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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
Protein Family And Group
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IPO4

Importin 4

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus By similarity. Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

Gene Name: Importin 4
Synonyms: IPO4, Importin-4, IMP4B, Importin-4b, Ran-binding protein 4, RanBP4, Importin 4
Target Sequences: NM_024658 NP_078934.3 Q8TEX9

☰ Filters
IPO4 (11)
IHC (7)
WB (9)
IF (2)
IP (3)
IgG (6)
No (11)
Viewing 1-11 of 11 items
IPO4 Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using IPO4 Polyclonal Antibody at dilution of 1:50.
Select
Rabbit Polyclonal (IgG) to Human IPO4
Mouse, Human
ELISA, IHC, WB
Unconjugated
20µl   0.3mg/ml   $205.00; 60µl   0.3mg/ml   $235.00; 120µl   0.3mg/ml   $295.00; 200µl   0.3mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human IPO4
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100µg   $335.00
IPO4 Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
Rabbit Polyclonal (IgG) to Human IPO4
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
IPO4 Antibody - Immunohistochemistry of paraffin-embedded Human prostate cancer using IPO4 Polyclonal Antibody at dilution of 1:50.
Select
Rabbit Polyclonal (IgG) to Human IPO4
Mouse, Human
ELISA, IHC, WB
Unconjugated
20µl   0.2mg/ml   $205.00; 60µl   0.2mg/ml   $235.00; 120µl   0.2mg/ml   $295.00; 200µl   0.2mg/ml   $395.00
IPO4 Antibody
Select
Rabbit Polyclonal to Human IPO4
Human
ELISA, IHC, WB
Unconjugated
100µg   1mg/ml   $265.00
IPO4 Antibody - Detection of Human Importin 4 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-Importin 4 used at a dilution of 1:5000 (0.2 ug/mg).
Select
Rabbit Polyclonal (IgG) to Human IPO4
Human
IHC, IP
Unconjugated
100µl   1mg/ml   $405.00
IPO4 Antibody - Detection of Human Importin 4 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-Importin 4 used at a dilution of 1:5000 (0.2 ug/mg).
Select
Rabbit Polyclonal (IgG) to Human IPO4
Human
IHC, IP
Unconjugated
100µl   1mg/ml   $405.00
IPO4 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human IPO4
Dog, Guinea pig, Horse, Bat, Human
WB
Unconjugated
100µl   0.5mg/ml   $365.00
IPO4 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human IPO4
Dog, Guinea pig, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
IPO4 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human IPO4
Dog, Guinea pig, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
Biotin Conjugated
100µl   1mg/ml   $385.00
IPO4 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human IPO4
Dog, Guinea pig, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
FITC Conjugated
100µl   1mg/ml   $385.00

Viewing 1-11 of 11 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).