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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Apg7 / ATG7

autophagy related 7

E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress. Plays also a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation.

Gene Name: autophagy related 7
Synonyms: ATG7, Apg7, APG7L, APG7-LIKE, Autophagy related 7, Autophagy-related protein 7, HAGP7, GSA7
Target Sequences: NM_006395 NP_006386.1 O95352

Publications (3)

1
Temporal orchestration of circadian autophagy rhythm by C/EBP. Ma D, Panda S, Lin JD. The EMBO journal. 2011 30:4642-51. [PubMed:21897364] [PMC:PMC3243590] Related Antibodies: LS-C156616.
2
Autophagy-Related Gene 7 Polymorphisms and Cerebral Palsy in Chinese Infants. Xia L, Xu J, Song J, Xu Y, Zhang B, Gao C, Zhu D, Zhou C, Bi D, Wang Y, Zhang X, Shang Q, Qiao Y, Wang X, Xing Q, Zhu C. Frontiers in cellular neuroscience. 2019 November;13: [Full Text Article] [PubMed:31749688] [PMC:PMC6848160]
3
Autophagy mediates HIF2 alpha degradation and suppresses renal tumorigenesis. Yao J, Tripathi DN, Ding Z, Xu Y, Sun M, Zhang J, Bai S, German P, Hoang A, Zhou L, Jonasch D, Zhang X, Conti CJ, Efstathiou E, Tannir NM, Eissa NT, Mills GB, Walker CL, Jonasch E. Oncogene. Jul; [Full Text Article] [PubMed:24998849] [PMC:PMC4286517] Related Antibodies: LS-B330.

Viewing 1-25 of 119 items
Apg7 / ATG7 Antibody - Anti-ATG7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $485.00
Apg7 / ATG7 Antibody - Anti-ATG7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Mouse, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
Apg7 / ATG7 Antibody - Anti-ATG7 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Mouse, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $545.00
Apg7 / ATG7 Antibody - Anti-ATG7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
50µg   $515.00
Apg7 / ATG7 Antibody - Anti-ATG7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Mouse, Human
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
50µg   $515.00
Apg7 / ATG7 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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Rabbit Polyclonal to Human Apg7 / ATG7
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Select
Sheep Polyclonal (IgG) to Human Apg7 / ATG7
Mouse, Rat, Human
IHC, WB
Unconjugated
500µg   $325.00
Apg7 / ATG7 Antibody - IHC ofAPG7L in formalin-fixed, paraffin-embedded human liver tissue using an isotype control (top) and Polyclonal Antibody to APG7L (bottom) at 5 ug/ml.
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Rabbit Polyclonal to Human Apg7 / ATG7
Human
IHC, IHC-P, WB
Unconjugated
100µg   0.5mg/ml   $335.00
Apg7 / ATG7 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
Rabbit Polyclonal to Human Apg7 / ATG7
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Apg7 / ATG7 Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with Autophagy APG7L antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
Rabbit Polyclonal to Human Apg7 / ATG7
Human
IF, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Select
Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Human
ELISA, Flo, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Apg7 / ATG7
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Apg7 / ATG7 Antibody - APG7L Antibody(D555) immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Rabbit Polyclonal to Human Apg7 / ATG7
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Apg7 / ATG7 Antibody - Immunohistochemistry analysis using Rabbit Anti-ATG10 Polyclonal Antibody. Tissue: Brain. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-ATG10 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X.
Select
Rabbit Polyclonal to Human Apg7 / ATG7
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100µg   1mg/ml   $365.00
Apg7 / ATG7 Antibody - Immunohistochemistry analysis using Rabbit Anti-ATG10 Polyclonal Antibody. Tissue: Brain. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-ATG10 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X.
Select
Rabbit Polyclonal to Human Apg7 / ATG7
Mouse, Rat, Human
IF, IHC, WB
PE, Atto 594 Conjugated
100µg   1mg/ml   $405.00
Apg7 / ATG7 Antibody - Immunohistochemistry analysis using Rabbit Anti-ATG10 Polyclonal Antibody. Tissue: Brain. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-ATG10 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X.
Select
Rabbit Polyclonal to Human Apg7 / ATG7
Mouse, Rat, Human
IF, IHC, WB
RPE Conjugated
100µg   1mg/ml   $395.00
Apg7 / ATG7 Antibody - Immunohistochemistry analysis using Rabbit Anti-ATG10 Polyclonal Antibody. Tissue: Brain. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-ATG10 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X.
Select
Rabbit Polyclonal to Human Apg7 / ATG7
Mouse, Rat, Human
IF, IHC, WB
PerCP Conjugated
100µg   1mg/ml   $395.00
Apg7 / ATG7 Antibody - Immunohistochemistry analysis using Rabbit Anti-ATG10 Polyclonal Antibody. Tissue: Brain. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-ATG10 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X.
Select
Rabbit Polyclonal to Human Apg7 / ATG7
Mouse, Rat, Human
IF, IHC, WB
Atto 390 Conjugated
100µg   1mg/ml   $405.00
Apg7 / ATG7 Antibody - Immunohistochemistry analysis using Rabbit Anti-ATG10 Polyclonal Antibody. Tissue: Brain. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-ATG10 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X.
Select
Rabbit Polyclonal to Human Apg7 / ATG7
Mouse, Rat, Human
IF, IHC, WB
Atto 488 Conjugated
100µg   1mg/ml   $395.00
Apg7 / ATG7 Antibody - Immunohistochemistry analysis using Rabbit Anti-ATG10 Polyclonal Antibody. Tissue: Brain. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-ATG10 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X.
Select
Rabbit Polyclonal to Human Apg7 / ATG7
Mouse, Rat, Human
IF, IHC, WB
Atto 633 Conjugated
100µg   1mg/ml   $395.00

Viewing 1-25 of 119 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).