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Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).
Gene Name: | Nicotinate Phosphoribosyltransferase Domain Containing 1 |
Synonyms: | NAPRT, FHA-HIT-interacting protein, NAPRTase, NAPRT1, PP3856, FHIP |
Target Sequences: | AF258565 AAG23768.1 Q6XQN6 |
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