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SLC19A3

solute carrier family 19 (thiamine transporter), member 3

SLC19A3 is a ubiquitously expressed transmembrane thiamine transporter that lacks folate transport activity. Mutations in this gene cause biotin-responsive basal ganglia disease (BBGD); a recessive disorder manifested in childhood that progresses to chronic encephalopathy, dystonia, quadriparesis, and death if untreated. Patients with BBGD have bilateral necrosis in the head of the caudate nucleus and in the putamen. Administration of high doses of biotin in the early progression of the disorder eliminates pathological symptoms while delayed treatment results in residual paraparesis, mild mental retardation, or dystonia. Administration of thiamine is ineffective in the treatment of this disorder. Experiments have failed to show that this protein can transport biotin. Mutations in this gene also cause a Wernicke's-like encephalopathy.

Gene Name: solute carrier family 19 (thiamine transporter), member 3
Family/Subfamily: Transporter , Reduced folate carrier
Synonyms: SLC19A3, Thiamine transporter 2, ThTr-2, THMD2, BBGD, THTR2
Target Sequences: NM_025243 NP_079519.1 Q9BZV2

☰ Filters
Antibodies (20)
Proteins (4)
Over-Expression Lysate (2)
Primary (20)
Recombinant (2)
SLC19A3 (24)
Human (20)
Mouse (5)
Rat (1)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (4)
Rabbit (4)
IHC-P (1)
WB (16)
ELISA (13)
IF (1)
IP (1)
rabbit (20)
IgG (15)
polyclonal pc (20)
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (8)
aa217-246 (8)
aa287-336 (4)
No (24)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
SLC19A3 Antibody - Immunofluorescence staining of HepG2 cells diluted at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The Secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
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SLC19A3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$284; 100 µg/$348
Select
SLC19A3 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$284; 100 µg/$348
Select
SLC19A3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$284; 100 µg/$348
Select
SLC19A3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$284; 100 µg/$348
Select
SLC19A3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
Select
SLC19A3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µl/$369; 200 µl/$411
Select
SLC19A3 Rabbit anti-Human Polyclonal (aa217-246) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$642
Select
SLC19A3 Rabbit anti-Human Polyclonal (aa217-246) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$825
Select
SLC19A3 Rabbit anti-Human Polyclonal (aa217-246) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$825
Select
SLC19A3 Rabbit anti-Human Polyclonal (aa217-246) (AP) Antibody
Human
ELISA, WB
AP Conjugated
200 µl/$825
Select
SLC19A3 Rabbit anti-Human Polyclonal (aa217-246) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$825
Select
SLC19A3 Rabbit anti-Human Polyclonal (aa217-246) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$825
Select
SLC19A3 Rabbit anti-Human Polyclonal (aa217-246) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$825
Select
SLC19A3 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$333; 200 µl/$429
SLC19A3 Antibody - SLC19A3 antibody Western blot of DU145 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC19A3 Rabbit anti-Human Polyclonal (aa287-336) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Human
WB
Unconjugated
100 µl/$414
SLC19A3 Antibody - SLC19A3 antibody Western blot of DU145 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC19A3 Rabbit anti-Human Polyclonal (aa287-336) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Human, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$459
SLC19A3 Antibody - SLC19A3 antibody Western blot of DU145 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC19A3 Rabbit anti-Human Polyclonal (aa287-336) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Human, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$459
SLC19A3 Antibody - SLC19A3 antibody Western blot of DU145 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC19A3 Rabbit anti-Human Polyclonal (aa287-336) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Human, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$459
SLC19A3 Antibody - SLC19A3 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The SLC19A3 antibody detected the SLC19A3 protein (arrow).
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SLC19A3 Rabbit anti-Human Polyclonal (aa217-246) Antibody
Human
WB
Unconjugated
400 µl/$376
SLC19A3 Antibody - Immunochemical staining of human SLC19A3 in human kidney with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.
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SLC19A3 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
50 µl/$275; 100 µl/$312; 200 µl/$350
SLC19A3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$469; 25 µg/$630
SLC19A3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
55.5 kDa
20 µg/$130
SLC19A3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
55.5 kDa
100 µg/$458
SLC19A3 Protein - Purified recombinant protein SLC19A3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
55.5 kDa
20 µg/$1,005
Viewing 1-24 of 24 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).