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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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MUC4

mucin 4, cell surface associated

May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. The MUC4-ERBB2 complex causes site-specific phosphorylation of the ERBB2 'Tyr-1248'. In polarized epithelilal cells segragates ERBB2 and other ERBB receptors and prevents ERBB2 from acting as a coreceptor. The interaction with ERBB2 leads to enhanced expression of CDKN1B. The formation of a MUC4-ERBB2-ERBB3-NRG1 complex leads to down-regulation of CDKN1B, resulting in repression of apoptosis and stimulation of proliferation.

Gene Name: mucin 4, cell surface associated
Family/Subfamily: Mucin , not assigned-Mucin
Synonyms: MUC4, ASGP, HSA276359, Mucin-4, Testis mucin, Tracheobronchial mucin, Ascites sialoglycoprotein, MUC-4, Mucin 4, tracheobronchial
Target Sequences: NM_018406 Q99102


MUC4 Antibody - Anti-MUC4 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal to Human MUC4
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   0.56mg/ml   $425.00
Select
Mouse Monoclonal [clone 1G8] (IgG1) to Rat MUC4
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg   0.5mg/ml   $635.00
Select
Mouse Monoclonal (IgG1) to Rat MUC4
Mouse, Rat, Human
ELISA, IHC, WB
HRP Conjugated
100µl   $815.00
Select
Mouse Monoclonal (IgG1) to Rat MUC4
Mouse, Rat, Human
ELISA, IHC, WB
Biotin Conjugated
100µl   $815.00
Select
Mouse Monoclonal (IgG1) to Rat MUC4
Mouse, Rat, Human
ELISA, IHC, WB
FITC Conjugated
100µl   0.95mg/ml   $815.00
Select
Mouse Monoclonal (IgG1) to Rat MUC4
Mouse, Rat, Human
ELISA, IHC, WB
PE Conjugated
100µl   $815.00
Select
Mouse Monoclonal (IgG1) to Rat MUC4
Mouse, Rat, Human
ELISA, IHC, WB
AP Conjugated
100µl   $815.00
Select
Mouse Monoclonal (IgG1) to Rat MUC4
Mouse, Rat, Human
ELISA, IHC, WB
APC Conjugated
100µl   $815.00
MUC4 Antibody - MUC4 monoclonal antibody (M07), clone 5B12 Western blot of MUC4 expression in HeLa.
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Mouse Monoclonal [clone 5B12] (IgG2a,k) to Human MUC4
Human
ELISA, WB
Unconjugated
100µg   $365.00
MUC4 Antibody - IHC of MUC4 on an FFPE Colon Tissue
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Mouse Monoclonal [clone 8G7] (IgG1) to Human MUC4
Human
IHC-Fr, IHC-P
Unconjugated
0.1ml   $245.00; 0.5ml   $335.00; 1ml   $515.00
MUC4 Antibody - IHC of MUC4 on an FFPE Colon Tissue
Select
Mouse Monoclonal [clone 8G7] (IgG1) to Human MUC4
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3ml   $255.00; 7ml   $335.00; 15ml   $475.00
MUC4 Antibody - Western blot of recombinant MUC4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human MUC4
Human
WB
Unconjugated
100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $295.00; 500µl   0.5mg/ml   $425.00; 1ml   0.5mg/ml   $495.00
MUC4 Antibody - Western blot of recombinant MUC4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human MUC4
Human
WB
HRP Conjugated
200µl   0.5mg/ml   $335.00; 500µl   0.5mg/ml   $515.00; 1ml   0.5mg/ml   $650.00
MUC4 Antibody - Western blot of recombinant MUC4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human MUC4
Human
WB
Biotin Conjugated
200µl   0.5mg/ml   $305.00; 500µl   0.5mg/ml   $455.00; 1ml   0.5mg/ml   $545.00
MUC4 Antibody - Western blot of recombinant MUC4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human MUC4
Human
WB
APC Conjugated
200µl   0.1mg/ml   $425.00; 500µl   0.1mg/ml   $800.00; 1ml   0.1mg/ml   $995.00
MUC4 Antibody - Western blot of recombinant MUC4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human MUC4
Human
WB
PE Conjugated
200µl   0.1mg/ml   $590.00; 500µl   0.1mg/ml   $1,185.00; 1ml   0.1mg/ml   $1,485.00
Select
Rabbit Polyclonal (IgG) to Human MUC4
Human
ELISA, WB
Unconjugated
100µg   $375.00
Select
Rabbit Polyclonal to Human MUC4
Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
MUC4 Antibody - Western blot analysis of MUC4 using Jurkat whole cells lysates
Select
Rabbit Polyclonal (IgG) to Human MUC4
Human
ELISA, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal to Human MUC4
Mouse, Rat, Human
WB
Unconjugated
100µl   1mg/ml   $385.00
MUC4 Antibody - Western blot of lysates from HeLa, MCF-7 cell line (from left to right) with MUC4 (Mucin-4 alpha chain) Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.
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Rabbit Polyclonal to Human MUC4
Human
WB
Unconjugated
400µl   $325.00
MUC4 Antibody - Western blot analysis of MUC4 expression in HeLa (A); SP2/0 (B); PC12 (C) whole cell lysates.
Select
Rabbit Polyclonal to Human MUC4
Mouse, Rat, Human
WB
Unconjugated
100µl   1mg/ml   $245.00
MUC4 Antibody - MUC4 antibody Western blot. All lanes: Anti MUC4 at 0.5 ug/ml. WB: PC12 Whole Cell Lysate at 40 ug. Predicted band size: 234 kD . Observed band size: 234 kD.
Select
Rabbit Polyclonal to Human MUC4
Rat, Human
WB
Unconjugated
100µg   0.5mg/ml   $325.00
MUC4 Antibody - Fig-1: Western blot analysis of MUC4. Anti-MUC4 antibody was used at 2 µg/ml on MCF-7 lysate.
Select
Rabbit Polyclonal (IgG) to Human MUC4
Human
WB
Unconjugated
25µg   0.5mg/ml   $215.00; 100µg   0.5mg/ml   $335.00
Select
Mouse Monoclonal [clone 1D4B] (IgG) to Rat MUC4
Rat, Human
WB
Unconjugated
25µg   $385.00; 100µg   $475.00
Viewing 1-25 of 28 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).