ULBP2 / RAET1H

UL16 binding protein 2

Ligand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.

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Products

Proteins (13)

Type

Over-Expression Lysate (2)

Recombinant (11)

Target

ULBP2 / RAET1H (13)

Publications

No (13)

Tag

6His, C-terminus (2)

Fc, C-terminus (4)

GST (1)

GST, N-terminus + His, C-terminus (1)

His (2)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (12)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Human Cells (3)

Mammalian Cells (3)

Wheat Germ Extract (1)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (7)

Biologically Active

Biologically active (1)

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Human ULBP2 / RAET1H Protein (Recombinant GST) (Full Length) - LS-G35435

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

52.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ULBP2 / RAET1H Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G144842

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

53.2 kDa

Price:

50 µg/$419

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Human ULBP2 / RAET1H Protein (Recombinant His-T7) (aa2-246) - LS-G26146

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.5 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Human ULBP2 / RAET1H Protein (Recombinant His) (Met1-Ser217) - LS-G98007

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

23.2 kDa

Price:

100 µg/$721

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Human ULBP2 / RAET1H Protein (Recombinant Fc, C-terminus) (Gly26-Ser217) - LS-G39478

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

51.4kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Human ULBP2 / RAET1H Protein (Recombinant 6His, C-terminus) (Gly26-Ser217) - LS-G39013

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

22.78kD

Price:

10 µg/$262; 50 µg/$365; 500 µg/$1,585; 1 mg/$2,157

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Human ULBP2 / RAET1H Protein (Recombinant Fc, C-terminus) (Met1-Ser217) - LS-G137982

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48.7 kDa

Price:

100 µg/$600

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Human ULBP2 / RAET1H Protein (Recombinant His) - LS-G1811

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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ULBP2 / RAET1H Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109522

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.2 kDa

Price:

100 µg/$494

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Human ULBP2 / RAET1H Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86798

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.2 kDa

Price:

20 µg/$150

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Human ULBP2 / RAET1H Protein (Recombinant 6His, C-terminus) (Gly26-Ser217) - LS-G138894

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

22.8 kDa

Price:

10 µg/$262; 50 µg/$361

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Human ULBP2 / RAET1H Protein (Recombinant Fc, C-terminus) - LS-G136797

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

51.4 kDa

Price:

50 µg/$453; 10 µg/$303; 1 mg/$2,837; 500 µg/$1,987

Select

Human ULBP2 / RAET1H Protein (Recombinant Fc, C-terminus) (Gly26-Ser217) - LS-G139129

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

51.4 kDa

Price:

10 µg/$281; 50 µg/$389

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