Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during trancription initiation such as preinitiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
|Gene Name:||TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa|
|Synonyms:||TAF1B, SL1, 63kD subunit, MGC:9349, RAF1B, RAFI63, SL1, TAFI63, TBP-associated factor 1B|
|Target Sequences:||L39061 AAA62863.1 Q53T94|
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