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TAF10

TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.

Gene Name: TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
Synonyms: TAF10, STAF28, TAF2H, TAFII-30, TAF(II)30, TAF2A, TAFII30
Target Sequences: NM_006284 NP_006275.1 Q12962

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
TAF10 (6)
No (6)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
TAF10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21.5 kDa
100 µg/$494
TAF10 Protein - 12.5% SDS-PAGE of human TAF10 stained with Coomassie Blue
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Wheat Germ Extract
GST
48.1 kDa
10 µg/$479; 25 µg/$670
TAF10 Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
TAF10 Protein - Purified recombinant protein TAF10 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
21.5 kDa
20 µg/$1,107
TAF10 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TAF10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
21.5 kDa
20 µg/$150
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).