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TADA3 / ADA3

transcriptional adaptor 3

DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene.

Gene Name: transcriptional adaptor 3
Synonyms: TADA3, ADA3 homolog, ADA3, ADA3-like protein, HADA3, NGG1, STAF54, TADA3L, Transcriptional adapter 3-like, Transcriptional adaptor 3, Transcriptional adapter 3
Target Sequences: NM_006354 NP_006345.1 O75528

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Products
Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
TADA3 / ADA3 (10)
No (10)
GST (3)
His (1)
Myc-DDK (Flag) (6)
Human (8)
293T Cells (2)
E. coli (2)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (2)
TADA3 / ADA3 Protein
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GST
37.84kDa
10 µg/$479; 25 µg/$670
TADA3 / ADA3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
41.2 kDa
100 µg/$494
TADA3 / ADA3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
48.7 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
41.2 kDa
20 µg/$150
TADA3 / ADA3 Protein
Select
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
Select
E. coli
GST
54.3 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
TADA3 / ADA3 Protein - 12.5% SDS-PAGE of human TADA3L stained with Coomassie Blue
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Wheat Germ Extract
GST
73.26 kDa
10 µg/$479; 25 µg/$670
TADA3 / ADA3 Protein - Purified recombinant protein TADA3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
41.2 kDa
20 µg/$1,107
TADA3 / ADA3 Protein - Purified recombinant protein TADA3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
48.7 kDa
20 µg/$1,107
TADA3 / ADA3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
48.7 kDa
100 µg/$494
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).