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SYTL4 / Granuphilin is a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein.
Gene Name: | synaptotagmin-like 4 |
Synonyms: | SYTL4, Exophilin-2, Granuphilin, Synaptotagmin-like 4, Granuphilin-a, SLP4, Synaptotagmin-like protein 4 |
Target Sequences: | Q96C24 Q96C24 |
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