SYNE4 / C19orf46

spectrin repeat containing, nuclear envelope family member 4

As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning By similarity. Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

SYNE4 / C19orf46 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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SYNE4 / C19orf46 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120405

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.3 kDa

Price:

100 µg/$494

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Human SYNE4 / C19orf46 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84572

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.3 kDa

Price:

20 µg/$150

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Human SYNE4 / C19orf46 Protein (Recombinant GST) (Full Length) - LS-G36851

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

57.4 kDa

Price:

10 µg/$479; 25 µg/$670

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