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SWAP70

SWAP switching B-cell complex 70kDa subunit

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

Gene Name:	SWAP switching B-cell complex 70kDa subunit
Synonyms:	SWAP70, KIAA0640, HSPC321, SWAP-70, Switch-associated protein 70
Target Sequences:	NM_015055 NP_055870.2 Q9UH65

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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