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SUMO3

small ubiquitin-like modifier 3

Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.

Gene Name: small ubiquitin-like modifier 3
Synonyms: SUMO3, SMT3A, SMT3 homolog 1, Smt3B, SMT3H1, SUMO-2, SUMO-3, Ubiquitin-like protein SMT3A, Ubiquitin-like protein SMT3B
Target Sequences: NM_006936 NP_008867.2 P55854

Publications (1)

1
Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl. Wu N, Kong X, Ji Z, Zeng W, Potts PR, Yokomori K, Yu H. Genes & development. 2012 26:1473-85. [PubMed:22751501] [PMC:PMC3403015] Related Antibodies: LS-C96462.

☰ Filters
Products
Proteins (12)
Over-Expression Lysate (2)
Recombinant (10)
SUMO3 (12)
No (12)
6His, C-terminus (2)
6His, N-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (11)
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (6)
SUMO3 Protein - Purified recombinant protein SUMO3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
11.5 kDa
20 µg/$1,107
SUMO3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
11.5 kDa
100 µg/$494
SUMO3 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
11.6kD
10 µg/$233; 50 µg/$277; 500 µg/$725; 1 mg/$1,113
SUMO3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
13.8kD
10 µg/$218; 50 µg/$233; 500 µg/$355; 1 mg/$416
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
11.1kD
10 µg/$255; 50 µg/$321; 500 µg/$1,262; 1 mg/$1,627
Select
293T Cells
Myc-DDK (Flag)
11.5 kDa
20 µg/$150
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
11.1 kDa
10 µg/$255; 50 µg/$317
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
13.8 kDa
10 µg/$220; 50 µg/$233
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
11.6 kDa
10 µg/$233; 50 µg/$277
SUMO3 Protein - 12.5% SDS-PAGE of human SUMO3 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
36.96 kDa
10 µg/$479; 25 µg/$670
Viewing 1-12 of 12 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).