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SUMO3

small ubiquitin-like modifier 3

Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.

Gene Name: small ubiquitin-like modifier 3
Synonyms: SUMO3, SMT3A, SMT3 homolog 1, Smt3B, SMT3H1, SUMO-2, SUMO-3, Ubiquitin-like protein SMT3A, Ubiquitin-like protein SMT3B
Target Sequences: NM_006936 NP_008867.2 P55854

Publications (1)

1
Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl. Wu N, Kong X, Ji Z, Zeng W, Potts PR, Yokomori K, Yu H. Genes & development. 2012 26:1473-85. [PubMed:22751501] [PMC:PMC3403015] Related Antibodies: LS-C96462.

☰ Filters
Antibodies (37)
Proteins (12)
Over-Expression Lysate (2)
Primary (37)
Recombinant (10)
SUMO3 (49)
Human (37)
Mouse (13)
Rat (12)
Bat (3)
Bovine (4)
Chicken (4)
Chimpanzee (6)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Pig (4)
Rabbit (4)
Sheep (1)
Xenopus (3)
Zebrafish (4)
IHC (5)
IHC-P (2)
WB (33)
ELISA (16)
IF (6)
Peptide-ELISA (1)
rabbit (29)
mouse (8)
Product Group
IHCPlus (1)
IgG (18)
IgG1 (7)
IgG2b,k (1)
monoclonal mc (8)
polyclonal pc (29)
4B9 (1)
76AT630.91.31 (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (18)
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aa6-55 (4)
N-Terminus (2)
aa2-103 (1)
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6His, N-terminus (2)
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GST, N-terminus (1)
His (1)
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Human (11)
293T Cells (1)
E. coli (5)
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Low endotoxin level (6)
SUMO3 Antibody - Western blot of anti-Beta-actin Monoclonal Antibody in HL-60 cell line lysates (37 ug/lane). Beta-actin (arrow) was detected using the purified antibody.
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SUMO3 Mouse anti-Human Monoclonal (76AT630.91.31) Antibody
Human
WB
Unconjugated
400 µl/$393
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SUMO3 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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SUMO3 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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SUMO3 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
SUMO3 Mouse anti-Human Monoclonal (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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SUMO3 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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SUMO3 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
SUMO3 Antibody - Anti-SUMO3 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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SUMO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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SUMO3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
0.1 mg/$379
SUMO3 Antibody - Immunohistochemistry of paraffin-embedded human ovarian cancer at dilution of 1:100
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SUMO3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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SUMO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SUMO3 Antibody - Anti-Human SUMO-3 Antibody - Western Blot. Western blot analysis is shown using Affinity Purified anti-Human SUMO-3 antibody to detect GFP-SUMO fusion proteins (arrowheads). Panel A. Increasing concentrations of human GFP-SUMO-3 were run on a SDS-PAGE, transferred onto nitrocellulose, and blocked for 1 hour with 5% non-fat dry milk in TTBS, and probed overnight at 4°C with a 1:1000 dilution of anti-hSUMO-3 antibody in 5% non-fat dry milk in TTBS. Detection occurred using a 1:1000 dilution of HRP-labeled Donkey anti-Rabbit IgG for 1 hour at room temperature. A chemiluminescence system was used for signal detection (Roche). Panel B. Specificity of the antibody was confirmed by SDS-PAGE of 5 ug of various GFP-SUMO constructs followed by transfer onto nitrocellulose. Lanes: 1. MW marker, 2. GFP-human SUMO-3, 3. GFP-human SUMO-1, 4. GFP-yeast SUMO, 5. GFP-Arabidopsis thaliana, SUMO-1, 6. GFP- Arabidopsis thaliana SUMO-2, 7. GFP-tomato SUMO. After blocking for 1 hour with 5% non-fat dry milk in TTBS, the blot was probed overnight at 4°C with anti-hSUMO-3 antibody diluted and detected as above. Only the human GFP-SUMO-3 band was visualized by chemiluminescence, and no cross-reactivity with other SUMO family members was observed.
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SUMO3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
500 µg/$606
SUMO3 Antibody
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SUMO3 Rabbit anti-Human Polyclonal (aa2-103) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
SUMO3 Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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SUMO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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SUMO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
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SUMO3 Mouse anti-Human Monoclonal (4B9) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
SUMO3 Antibody - Immunofluorescence analysis of U-2OS cells using SUMO3 Polyclonal Antibody at dilution of 1:100.Blue: DAPI for nuclear staining.
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SUMO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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SUMO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
SUMO3 Antibody - SUMO3 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SUMO3 Rabbit anti-Mouse Polyclonal (aa6-55) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
SUMO3 Antibody - SUMO3 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SUMO3 Rabbit anti-Mouse Polyclonal (aa6-55) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Guinea pig, Bovine, Bat, Pig, Horse, Rat, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
SUMO3 Antibody - SUMO3 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SUMO3 Rabbit anti-Mouse Polyclonal (aa6-55) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Guinea pig, Bovine, Bat, Pig, Horse, Rat, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
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SUMO3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µg/$786
SUMO3 Antibody - Western blot analysis of SUMO3 expression in HeLa (A); Raw264.7 (B); PC12 (C) whole cell lysates.
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SUMO3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Zebrafish, Pig, Rabbit, Mouse, Sheep, Bovine, Rat, Human
WB
Unconjugated
100 µl/$299
SUMO3 Antibody - Western blot of SUMO3 antibody at 1:500 dilution. Lane 1: HeLa whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
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SUMO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
SUMO3 Antibody - SUMO3 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SUMO3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Viewing 1-25 of 49 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).