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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SUMO3

small ubiquitin-like modifier 3

Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.

Gene Name: small ubiquitin-like modifier 3
Synonyms: SUMO3, SMT3A, SMT3 homolog 1, Smt3B, SMT3H1, SUMO-2, SUMO-3, Ubiquitin-like protein SMT3A, Ubiquitin-like protein SMT3B
Target Sequences: NM_006936 NP_008867.2 P55854

Publications (1)

1
Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl. Wu N, Kong X, Ji Z, Zeng W, Potts PR, Yokomori K, Yu H. Genes & development. 2012 26:1473-85. [PubMed:22751501] [PMC:PMC3403015] Related Antibodies: LS-C96462.

Viewing 1-25 of 41 items
SUMO3 Antibody - Anti-SUMO3 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human SUMO3
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $545.00
SUMO3 Antibody - Western blot of anti-Beta-actin Monoclonal Antibody in HL-60 cell line lysates (37 ug/lane). Beta-actin (arrow) was detected using the purified antibody.
Select
(1) Publication(s)
Mouse Monoclonal [clone 76AT630.91.31] (IgG1) to Human SUMO3
Human
WB
Unconjugated
400µl   $325.00
Select
Mouse Monoclonal (IgG1) to Human SUMO3
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Mouse Monoclonal (IgG1) to Human SUMO3
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Mouse Monoclonal (IgG1) to Human SUMO3
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Mouse Monoclonal (IgG1) to Human SUMO3
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Mouse Monoclonal (IgG1) to Human SUMO3
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Mouse Monoclonal (IgG1) to Human SUMO3
Human
ELISA, WB
PE Conjugated
200µl   $740.00
Select
Mouse Monoclonal (IgG1) to Human SUMO3
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal to Human SUMO3
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg   0.5mg/ml   $315.00
SUMO3 Antibody - Immunohistochemistry of paraffin-embedded human ovarian cancer at dilution of 1:100
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Rabbit Polyclonal (IgG) to Human SUMO3
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human SUMO3
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
SUMO3 Antibody - Immunofluorescence staining of SUMO3 in A549 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human SUMO3 polyclonal antibody (dilution ratio 1:1000) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to cytoplasm and nucleus.
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Rabbit Polyclonal (IgG) to Human SUMO3
Human
ICC, IF, WB
Unconjugated, Preservative Free
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
SUMO3 Antibody
Select
Rabbit Polyclonal to Human SUMO3
Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $255.00
SUMO3 Antibody
Select
Rabbit Polyclonal (IgG) to Human SUMO3
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal to Human SUMO3
Mouse, Rat, Human
IF, WB
Unconjugated
100µl   1mg/ml   $385.00
SUMO3 Antibody - Western blot analysis of extracts of various cell lines, using SUMO3 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
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Rabbit Polyclonal (IgG) to Human SUMO3
Mouse, Human
IF, WB
Unconjugated
100µl   $295.00; 200µl   $385.00
Select
Mouse Monoclonal [clone 4B9] (IgG2b,k) to Human SUMO3
Human
ELISA, WB
Unconjugated
100µg   $365.00
Select
Rabbit Polyclonal to Human SUMO3
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
SUMO3 Antibody - Anti-Human SUMO-3 Antibody - Western Blot. Western blot analysis is shown using Affinity Purified anti-Human SUMO-3 antibody to detect GFP-SUMO fusion proteins (arrowheads). Panel A. Increasing concentrations of human GFP-SUMO-3 were run on a SDS-PAGE, transferred onto nitrocellulose, and blocked for 1 hour with 5% non-fat dry milk in TTBS, and probed overnight at 4°C with a 1:1000 dilution of anti-hSUMO-3 antibody in 5% non-fat dry milk in TTBS. Detection occurred using a 1:1000 dilution of HRP-labeled Donkey anti-Rabbit IgG for 1 hour at room temperature. A chemiluminescence system was used for signal detection (Roche). Panel B. Specificity of the antibody was confirmed by SDS-PAGE of 5 ug of various GFP-SUMO constructs followed by transfer onto nitrocellulose. Lanes: 1. MW marker, 2. GFP-human SUMO-3, 3. GFP-human SUMO-1, 4. GFP-yeast SUMO, 5. GFP-Arabidopsis thaliana, SUMO-1, 6. GFP- Arabidopsis thaliana SUMO-2, 7. GFP-tomato SUMO. After blocking for 1 hour with 5% non-fat dry milk in TTBS, the blot was probed overnight at 4°C with anti-hSUMO-3 antibody diluted and detected as above. Only the human GFP-SUMO-3 band was visualized by chemiluminescence, and no cross-reactivity with other SUMO family members was observed.
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Rabbit Polyclonal to Human SUMO3
Human
ELISA, WB
Unconjugated
500µg   5mg/ml   $475.00
SUMO3 Antibody - SUMO3 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Mouse SUMO3
Xenopus, Chicken, Zebrafish, Pig, Horse, Rabbit, Mouse, Guinea pig, Bovine, Bat, Rat, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
Select
Rabbit Polyclonal to Human SUMO3
Human
WB
Unconjugated
100µg   $635.00
SUMO3 Antibody - Western blot of SUMO3 antibody at 1:500 dilution. Lane 1: HeLa whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
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Rabbit Polyclonal to Human SUMO3
Mouse, Rat, Human
WB
Unconjugated
100µl   1mg/ml   $385.00
SUMO3 Antibody - SUMO3 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human SUMO3
Human
WB
Unconjugated
100µl   0.5mg/ml   $365.00
SUMO3 Antibody - Western blot of SUMO3 (SMT3) in human testis lysate in the 1) absence, 2) presence of immunizing peptide and 3) mouse testis lysate using SUMO3 antibody at 2 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.
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Rabbit Polyclonal to Human SUMO3
Mouse, Horse, Human, Monkey
WB
Unconjugated
100µg   $335.00

Viewing 1-25 of 41 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).