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Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.
Gene Name: | syntaxin binding protein 2 |
Synonyms: | STXBP2, Hunc18b, MUNC18-2, Protein unc-18 homolog B, UNC18B, Pp10122, Syntaxin binding protein 2, Syntaxin-binding protein 2, Protein unc-18 homolog 2, Unc-18B, UNC18-2 |
Target Sequences: | NM_006949 NP_008880.2 Q15833 |
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