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STXBP1 / MUNC18-1
syntaxin binding protein 1
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
| Gene Name: | syntaxin binding protein 1 |
| Synonyms: | STXBP1, EIEE4, HUNC18, MUNC18-1, N-Sec1, NSEC1, Protein unc-18 homolog 1, Protein unc-18 homolog A, UNC18, Unc18-1, p67, RBSEC1, Unc-18A, Munc18, Neuronal SEC1, Syntaxin binding protein 1, Syntaxin-binding protein 1, UNC18A |
| Target Sequences: | NM_003165 NP_003156.1 P61764 |
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