STRADB / ALS2CR2

STE20-related kinase adaptor beta

STRADB / ALS2CR2 is a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

STRADB / ALS2CR2 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (2)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (3)

Purification

Purified (1)

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STRADB / ALS2CR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101580

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

100 µg/$494

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Human STRADB / ALS2CR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91032

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

20 µg/$150

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Human STRADB / ALS2CR2 Protein (Recombinant GST, N-terminus) (aa319-418) - LS-G62694

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human STRADB / ALS2CR2 Protein (Recombinant GST, N-terminus) (aa1-95) - LS-G62698

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human STRADB / ALS2CR2 Protein (Recombinant GST) (Full Length) - LS-G34310

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

71.72 kDa

Price:

10 µg/$479; 25 µg/$670

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