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STRADB / ALS2CR2

STE20-related kinase adaptor beta

STRADB / ALS2CR2 is a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: STE20-related kinase adaptor beta
Family/Subfamily: Protein Kinase , STLK
Synonyms: STRADB, ALS2CR2, CALS-21, ILP-interacting protein ILPIPA, ILPIP, ILP-interacting protein, PAPK, Pseudokinase ALS2CR2, PRO1038, ILPIPA, STRAD beta
Target Sequences: NM_018571 NP_061041.2 Q9C0K7

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
STRADB / ALS2CR2 (5)
No (5)
GST (1)
GST, N-terminus (2)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (3)
Purified (1)
STRADB / ALS2CR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
46.8 kDa
100 µg/$494
STRADB / ALS2CR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
46.8 kDa
20 µg/$150
STRADB / ALS2CR2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
STRADB / ALS2CR2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
STRADB / ALS2CR2 Protein - 12.5% SDS-PAGE of human STRADB stained with Coomassie Blue
Select
Wheat Germ Extract
GST
71.72 kDa
10 µg/$479; 25 µg/$670
Viewing 1-5 of 5 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).