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SSX4

synovial sarcoma, X breakpoint 4

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: synovial sarcoma, X breakpoint 4
Synonyms: SSX4, CT5.4, Cancer/testis antigen 5.4, Protein SSX4, SSX4A, SSX4B
Target Sequences: NM_005636 NP_005627.1 O60224

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Products
Proteins (10)
Over-Expression Lysate (6)
Recombinant (4)
SSX4 (10)
No (10)
GST (1)
GST, N-terminus (2)
Myc-DDK (Flag) (7)
Human (7)
293T Cells (3)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (2)
SSX4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21.7 kDa
100 µg/$494
SSX4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
17.7 kDa
100 µg/$494
SSX4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
17.7 kDa
100 µg/$494
SSX4 Protein - 12.5% SDS-PAGE of human SSX4 stained with Coomassie Blue
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Wheat Germ Extract
GST
48.3 kDa
10 µg/$479; 25 µg/$670
SSX4 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
SSX4 Protein - Purified recombinant protein SSX4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
21.7 kDa
20 µg/$1,107
SSX4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SSX4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
17.7 kDa
20 µg/$150
SSX4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
21.7 kDa
20 µg/$150
SSX4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
17.7 kDa
20 µg/$150
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).