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SSX1

synovial sarcoma, X breakpoint 1

SSX1 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X.

Gene Name: synovial sarcoma, X breakpoint 1
Synonyms: SSX1, Cancer/testis antigen 5.1, CT5.1, Protein SSX1, SSRC
Target Sequences: NM_005635 NP_005626.1 Q16384

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
SSX1 (6)
No (6)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
SSX1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21.8 kDa
100 µg/$494
SSX1 Protein
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E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
SSX1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SSX1 Protein - Purified recombinant protein SSX1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
21.8 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
21.8 kDa
20 µg/$150
SSX1 Protein - 12.5% SDS-PAGE of human SSX1 stained with Coomassie Blue
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Wheat Germ Extract
GST
48.3 kDa
10 µg/$479; 25 µg/$670
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).