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Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.
Gene Name: | somatostatin receptor 4 |
Family/Subfamily: | GPCR , Somatostatin |
Synonyms: | SSTR4, Fourth somatostatin receptor, SS-4-R, SS4R, Somatostatin receptor type 4, Sst4 receptor, SST4, Somatostatin receptor 4, SS4-R |
Target Sequences: | NM_001052 NP_001043.2 P31391 |
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