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SST / Somatostatin

somatostatin

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells.

Gene Name: somatostatin
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: SST, Somatostatin-28, SMST, Somatostatin-14, Somatostatin
Target Sequences: NM_001048 NP_001039.1 P61278

Publications (6)

1
Characterization of Autonomic Nerve Markers and Lymphocyte Subsets in the Ileal Peyer’s Patch of Pigs Infected Experimentally with Brachyspira hyodysenteriae. J. Kaleczyc, P. Podlasz, A. Winnick, W. Wasowicz, W. Sienkiewicz, J. Zmudzki and M. Lakomy. Journal of comparative pathology. 2010 143:248-57. (IHC-Fr; Pig) [Full Text Article] [PubMed:20605161]
2
A smad signaling network regulates islet cell proliferation. El-Gohary Y, Tulachan S, Wiersch J, Guo P, Welsh C, Prasadan K, Paredes J, Shiota C, Xiao X, Wada Y, Diaz M, Gittes G. Diabetes. 2014 63:224-36. (IHC-P; Human) [Full Text Article] [PubMed:24089514] [PMC:PMC3868054]
3
Establishment of a diabetes mellitus type 1 model in the common marmoset. Yuan W, Fukuda S, Inoue T, Okochi H, Sasaki E, Shimoda M. Science advances. 2019 October;9:14546. [Full Text Article] [PubMed:31601983] [PMC:PMC6787219]
4
Disinhibition of somatostatin-positive GABAergic interneurons results in an anxiolytic and antidepressant-like brain state. T Fuchs, S J Jefferson, A Hooper, P-Hp Yee, J Maguire, B Luscher. Molecular psychiatry. 2017 June;22:920-930. [Full Text Article] [PubMed:27821870] [PMC:PMC5422144]
5
Itch-associated Neuropeptides and Their Receptor Expression in Dog Dorsal Root Ganglia and Spinal Cord. Joshua J Wheeler, B Duncan Lascelles, Thierry Olivry, Santosh K Mishra. Acta dermato-venereologica. 2019 Nov;99:1131-1135. [Full Text Article] [PubMed:31449313]
6
Multifaceted secretion of htNSC-derived hypothalamic islets induces survival and antidiabetic effect via peripheral implantation in mice. Yizhe Tang , Juan Pablo Zuniga-Hertz , Cheng Han, Bin Yu, Dongsheng Cai. eLife. 2020 Feb;9:e52580. [Full Text Article] [PubMed:32081132] [PMC:PMC7062468]
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Antibodies (74)
Primary (74)
SST / Somatostatin (74)
Human (46)
Mouse (36)
Rat (37)
Bat (5)
Bovine (6)
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Xenopus (2)
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IHC (18)
IHC-Fr (6)
IHC-P (12)
WB (50)
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ELISA (15)
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IP (2)
Peptide-ELISA (2)
rabbit (57)
mouse (13)
rat (3)
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IgG2a,k (2)
IgG2b (3)
IgG2b,k (8)
monoclonal mc (16)
polyclonal pc (58)
7G5 (2)
ABT-SST (1)
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Unconjugated (38)
aa27-116 (16)
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10-90 aa, N-terminal (1)
Amino Acid: 1-116 (1)
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aa10-59 (1)
No (74)
SST / Somatostatin Antibody - Anti-Somatostatin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:20.
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SST / Somatostatin Rat anti-Human Monoclonal (Supernatant) (YC7) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated, Supernatant
0.1 ml/$495
SST / Somatostatin Antibody - Anti-SST / Somatostatin antibody IHC of human pancreas, islets of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Neuroscience
Cancer Pathology
SST / Somatostatin Rabbit anti-Human Polyclonal (aa10-59) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
SST / Somatostatin Antibody - IHC of paraffin-embedded pancreas tissues using SST mouse monoclonal antibody with DAB staining.
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SST / Somatostatin Mouse anti-Human Monoclonal (7G5) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$459
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SST / Somatostatin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Pig, Human
IF, IHC
Unconjugated
50 µl/$572
SST / Somatostatin Antibody - Western Blot; Sample: Recombinant SST, Human.
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SST / Somatostatin Rabbit anti-Human Polyclonal (aa1-116) Antibody
Rat, Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
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SST / Somatostatin Sheep Polyclonal Antibody
Unconjugated
1 mg/$269
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SST / Somatostatin Rat Monoclonal (aa1-14) (YC7) Antibody
Human
IHC
Unconjugated
100 µl/$786
SST / Somatostatin Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Neuroscience
Cancer Pathology
SST / Somatostatin Rabbit anti-Human Polyclonal (aa1-14) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$460
SST / Somatostatin Antibody - Immunohistochemical analysis of Somatostatin staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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SST / Somatostatin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Sheep, Bovine, Rat, Pig, Mouse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$299
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SST / Somatostatin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Pig, Human
ELISA
Unconjugated
400 µg/$878
SST / Somatostatin Antibody - Western blot of recombinant SST / Somatostatin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SST / Somatostatin Rabbit anti-Mouse Polyclonal (aa27-116) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
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SST / Somatostatin Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
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SST / Somatostatin Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452; 1000 µg/$586
SST / Somatostatin Antibody - Somatostatin Antibody in Immunohistochemistry (IHC)
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SST / Somatostatin Mouse anti-Human Monoclonal (Amino Acid: 1-116) (7G5) Antibody
Mouse, Human
Flo, IHC, WB
Unconjugated
100 µg/$503
SST / Somatostatin Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
SST / Somatostatin Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
SST / Somatostatin Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
SST / Somatostatin Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
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SST / Somatostatin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Pig, Human
IF, IHC
Unconjugated
50 µl/$572
SST / Somatostatin Antibody - Western blot of Somatostatin antibody
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SST / Somatostatin Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SST / Somatostatin Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using Somatostatin antibody.
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SST / Somatostatin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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SST / Somatostatin Rat anti-Human Monoclonal Antibody
Rat, Human
IHC, IHC-Fr, IHC-P
Unconjugated
200 µl/$748
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SST / Somatostatin Rabbit anti-Human Polyclonal (Concentrated) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated, Concentrated
1 ml/$791
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SST / Somatostatin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$341
SST / Somatostatin Antibody - Immunohistochemistry of paraffin-embedded human testis tissue using SST Antibody at dilution of 1:100
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SST / Somatostatin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
SST / Somatostatin Antibody - Immunohistochemistry of paraffin-embedded Human brain tissue  using SST Polyclonal Antibody at dilution of 1:60(×200)
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SST / Somatostatin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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SST / Somatostatin Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).