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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Fax: +1 (206) 577-4565
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SSB / La
Sjogren syndrome antigen B (autoantigen La)
SSB / La is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
| Gene Name: | Sjogren syndrome antigen B (autoantigen La) |
| Synonyms: | SSB, Autoantigen La, La, La ribonucleoprotein, Lupus La antigen, SS-B, SS-B/La protein, La autoantigen, LARP3, Lupus La protein |
| Target Sequences: | NM_003142 NP_003133.1 P05455 |
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