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SS18L1 / CREST

synovial sarcoma translocation gene on chromosome 18-like 1

Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP.

Gene Name: synovial sarcoma translocation gene on chromosome 18-like 1
Synonyms: SS18L1, LP2261, SS18-like protein 1, SYT homolog 1, CREST, KIAA0693
Target Sequences: NP_945173.1 O75177

☰ Filters
Antibodies (21)
Proteins (3)
Over-Expression Lysate (2)
Primary (21)
Recombinant (1)
SS18L1 / CREST (24)
Human (21)
Mouse (6)
Rat (6)
Chicken (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (4)
IHC (4)
IHC-P (1)
WB (17)
ELISA (12)
IF (1)
IP (1)
Peptide-ELISA (1)
rabbit (20)
mouse (1)
IgG (15)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (20)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (10)
aa272-300 (7)
aa251-300 (4)
No (24)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
SS18L1 / CREST Antibody - Sample (30 ug of whole cell lysate) A: MCF-7 10% SDS PAGE SS18L1 antibody diluted at 1:1000
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SS18L1 / CREST Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$450
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
SS18L1 / CREST Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution of 1:100
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SS18L1 / CREST Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
SS18L1 / CREST Antibody - Immunohistochemistry of paraffin-embedded Mouse brain using SS18L1 Polyclonal Antibody at dilution of 1:100 (40x lens).
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SS18L1 / CREST Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SS18L1 / CREST Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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SS18L1 / CREST Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
SS18L1 / CREST Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$361
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (aa272-300) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (aa272-300) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (aa272-300) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (aa272-300) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (aa272-300) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (aa272-300) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
SS18L1 / CREST Antibody - SS18L1 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (aa251-300) Antibody
Human
WB
Unconjugated
100 µl/$424
SS18L1 / CREST Antibody - SS18L1 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (aa251-300) (HRP) Antibody
Chicken, Mouse, Dog, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
SS18L1 / CREST Antibody - SS18L1 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (aa251-300) (Biotin) Antibody
Chicken, Mouse, Dog, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
SS18L1 / CREST Antibody - SS18L1 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal (aa251-300) (FITC) Antibody
Chicken, Mouse, Dog, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
SS18L1 / CREST Antibody - SS18L1 Antibody western blot of K562 cell line lysates (35 ug/lane). The SS18L1 antibody detected the SS18L1 protein (arrow).
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SS18L1 / CREST Rabbit anti-Human Polyclonal (aa272-300) Antibody
Human
WB
Unconjugated
400 µl/$393
SS18L1 / CREST Antibody - Western blot analysis of extract of various cells.
Select
SS18L1 / CREST Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
SS18L1 / CREST Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.8 kDa
20 µg/$150
SS18L1 / CREST Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SS18L1 / CREST Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
42.8 kDa
100 µg/$494
Viewing 1-24 of 24 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).