SRSF2 / SC35

serine/arginine-rich splicing factor 2

Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. Can bind to beta-globin mRNA and commit it to the splicing pathway. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment.

☰ Filters

Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

SRSF2 / SC35 (4)

Publications

No (4)

Tag

GST (1)

His-GST (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

Human SRSF2 / SC35 Protein (Recombinant His-GST) (aa14-221) - LS-G25555

Source:

E. coli

Tag:

His-GST

Molecular Weight:

54.1 kDa

Price:

10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142

Select

Human SRSF2 / SC35 Protein (Recombinant GST) (Full Length) - LS-G30380

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

45.43 kDa

Price:

10 µg/$479; 25 µg/$670

Select

SRSF2 / SC35 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117609

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.3 kDa

Price:

100 µg/$494

Select

Human SRSF2 / SC35 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78938

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.3 kDa

Price:

20 µg/$150

Viewing 1-4 of 4 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.