SRRT / ARS2

serrate RNA effector molecule homolog (Arabidopsis)

Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

SRRT / ARS2 (5)

Publications

No (5)

Tag

DDK,C-terminus (1)

GST (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Sf9 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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SRRT / ARS2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112983

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

100.5 kDa

Price:

100 µg/$710

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Human SRRT / ARS2 Protein (Recombinant DDK,C-terminus) - LS-G142489

Source:

Sf9 Cells

Tag:

DDK,C-terminus

Molecular Weight:

100.5 kDa

Price:

20 µg/$677

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Human SRRT / ARS2 Protein (Recombinant GST) (Full Length) - LS-G33832

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

72.82 kDa

Price:

2 µg/$439

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Human SRRT / ARS2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69989

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

100.5 kDa

Price:

20 µg/$1,107

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Human SRRT / ARS2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86005

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

100.5 kDa

Price:

20 µg/$215

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