Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

SRPK2

SRSF protein kinase 2

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation. Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28. Can mediate hepatitis B virus (HBV) core protein phosphorylation. Plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein but by reducing the packaging efficiency of the pregenomic RNA (pgRNA) without affecting the formation of the viral core particles.

Gene Name: SRSF protein kinase 2
Family/Subfamily: Protein Kinase , SRPK
Synonyms: SRPK2, H_RG152G17.1a, H_RG152G17.1b, SFRS protein kinase 2, SFRSK2, SRSF protein kinase 2, SR-protein-specific kinase 2, MSRPK2, SR protein kinase 2, WUGSC:H_RG152G17.1a, Serine kinase SRPK2
Target Sequences: U88666 AAC05299.1 P78362

☰ Filters
Products
Proteins (11)
Over-Expression Lysate (4)
Recombinant (7)
SRPK2 (11)
No (11)
GST (4)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (9)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (5)
Purified (4)
SRPK2 Protein - Purified recombinant protein SRPK2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
77.3 kDa
20 µg/$1,107
SRPK2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
78.8 kDa
100 µg/$710
SRPK2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
77.3 kDa
100 µg/$494
SRPK2 Protein - Recombinant  SRSF Protein Kinase 2 By SDS-PAGE
Select
E. coli
His-T7
30.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
SRPK2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SRPK2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
77.3 kDa
20 µg/$150
SRPK2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
78.8 kDa
20 µg/$215
SRPK2 Protein - 12.5% SDS-PAGE of human SRPK2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
101.42 kDa
10 µg/$479; 25 µg/$670
SRPK2 Protein - 12.5% SDS-PAGE of human SRPK2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
101.31 kDa
10 µg/$479; 25 µg/$670
SRPK2 Protein - 12.5% SDS-PAGE of human SRPK2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
105.4 kDa
10 µg/$479; 25 µg/$670
SRPK2 Protein - 12.5% SDS-PAGE of human SRPK2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
103.73 kDa
10 µg/$479; 25 µg/$670
Viewing 1-11 of 11 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).