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SREBF2 / SREBP2
sterol regulatory element binding transcription factor 2
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.
| Gene Name: | sterol regulatory element binding transcription factor 2 |
| Synonyms: | SREBF2, SREBP2, SREBP-2, BHLHd2 |
| Target Sequences: | NM_004599 NP_004590.2 Q12772 |
Publications (3)
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