SPTA1 / Alpha Spectrin

spectrin, alpha, erythrocytic 1 (elliptocytosis 2)

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.

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ELISA Kits (2)

Type

Sandwich (2)

Target

SPTA1 / Alpha Spectrin (2)

Reactivity

Human (1)

Mouse (1)

Format

96-Well Strip Plate (2)

Publications

No (2)

Sample Type

Plasma (2)

Serum (2)

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Human SPTA1 / Alpha Spectrin (Sandwich ELISA) ELISA Kit - LS-F66580

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse SPTA1 / Alpha Spectrin (Sandwich ELISA) ELISA Kit - LS-F66931

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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