SPACA1

sperm acrosome associated 1

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.

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Products

Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

SPACA1 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human SPACA1 Protein (Recombinant GST) (Full Length) - LS-G35535

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

58.5 kDa

Price:

10 µg/$479; 25 µg/$670

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SPACA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109317

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32 kDa

Price:

100 µg/$494

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Human SPACA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92005

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32 kDa

Price:

20 µg/$150

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