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SPA17 / Sperm Protein 17

sperm autoantigenic protein 17

SPA17 / Sperm Protein 17 is a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.

Gene Name: sperm autoantigenic protein 17
Synonyms: SPA17, Cancer/testis antigen 22, Sperm surface protein Sp17, SP17, SP17-1, Sperm protein 17, CT22, Sperm autoantigenic protein 17
Target Sequences: NM_017425 NP_059121.1 Q15506

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Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
SPA17 / Sperm Protein 17 (9)
No (9)
GST (2)
GST, N-terminus (1)
His (1)
His-T7 (3)
Myc-DDK (Flag) (2)
Human (6)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
SPA17 / Sperm Protein 17 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
17.2 kDa
20 µg/$150
SPA17 / Sperm Protein 17 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
17.2 kDa
100 µg/$494
SPA17 / Sperm Protein 17 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
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E. coli
GST
43.4 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
SPA17 / Sperm Protein 17 Protein - Recombinant Sperm Protein 17 By SDS-PAGE
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E. coli
His-T7
20.1 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
SPA17 / Sperm Protein 17 Protein - Recombinant Sperm Protein 17 By SDS-PAGE
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E. coli
His-T7
21.0 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
SPA17 / Sperm Protein 17 Protein - Recombinant Sperm Protein 17 By SDS-PAGE
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E. coli
His-T7
19.8 kDa
10 µg/$270; 50 µg/$372; 100 µg/$592; 200 µg/$742; 1 mg/$1,786; 500 µg/$1,352; 5 mg/$2,742; 2 mg/$1,966
SPA17 / Sperm Protein 17 Protein - 12.5% SDS-PAGE of human SPA17 stained with Coomassie Blue
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Wheat Germ Extract
GST
43.8 kDa
10 µg/$479; 25 µg/$670
SPA17 / Sperm Protein 17 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).