SORT1 / Sortilin

sortilin 1

Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.

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Products

ELISA Kits (8)

Type

Custom (1)

Sandwich (7)

Target

SORT1 / Sortilin (8)

Reactivity

Human (4)

Mouse (2)

Rat (2)

Format

96-Well Microplate (3)

96-Well Strip Plate (5)

Publications

No (8)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (3)

Plasma (4)

Serum (4)

Tissue Homogenates (3)

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Human SORT1 / Sortilin (Sandwich ELISA) ELISA Kit - LS-F21281

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse SORT1 / Sortilin (Sandwich ELISA) ELISA Kit - LS-F25393

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$854

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Human SORT1 / Sortilin (Sandwich ELISA) ELISA Kit - LS-F6828

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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Rat SORT1 / Sortilin (Sandwich ELISA) ELISA Kit - LS-F66884

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human SORT1 / Sortilin (Sandwich ELISA) ELISA Kit - LS-F50042

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.819 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$672

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Mouse SORT1 / Sortilin (Custom) ELISA Kit - LS-F66062

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$783

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Human SORT1 / Sortilin (Sandwich ELISA) ELISA Kit - LS-F66710

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

46.9 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Rat SORT1 / Sortilin (Sandwich ELISA) ELISA Kit - LS-F74366

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$646

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