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Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain.
Gene Name: | sorbin and SH3 domain containing 3 |
Synonyms: | SORBS3, SH3D4, SCAM-1, SCAM1, Vinexin |
Target Sequences: | NM_005775 NP_005766.3 O60504 |
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