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SNX14 is a member of the sorting nexin family. Members of this family have a phox (PX) phosphoinositide binding domain and are involved in intracellular trafficking. The encoded protein also contains a regulator of G protein signaling (RGS) domain. Regulator of G protein signaling family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. Alternate splicing results in transcript variants encoding distinct isoforms.
Gene Name: | Sorting Nexin 14 |
Synonyms: | SNX14, Sorting nexin 14, RP11-321N4.2, Sorting nexin-14, RGS-PX2 |
Target Sequences: | AA196446 |
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