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SNX13

sorting nexin 13

SNX13 is a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Gene Name: sorting nexin 13
Synonyms: SNX13, KIAA0713, Sorting nexin 13, RGS-PX1, Sorting nexin-13
Target Sequences: NM_015132 NP_055947.1 Q9Y5W8

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
SNX13 (5)
No (5)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
SNX13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
110.8 kDa
100 µg/$494
SNX13 Protein - Recombinant Sorting Nexin 13 By SDS-PAGE
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E. coli
His
26.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
SNX13 Protein - 12.5% SDS-PAGE of human SNX13 stained with Coomassie Blue
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Wheat Germ Extract
GST
137.4 kDa
2 µg/$439
SNX13 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SNX13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
110.8 kDa
20 µg/$150
Viewing 1-5 of 5 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).