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Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.
Gene Name: | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
Synonyms: | SNTB1, 59-DAP, A1B, Beta-1-syntrophin, Beta1-syntrophin, BSYN2, DAPA1B, SNT2B1, Tax interaction protein 43, SNT2, Syntrophin-2, TIP-43 |
Target Sequences: | NM_021021 NP_066301.1 Q13884 |
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