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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SNRPE

small nuclear ribonucleoprotein polypeptide E

Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.

Gene Name: small nuclear ribonucleoprotein polypeptide E
Synonyms: SNRPE, B-raf, Sm protein E, SME, SnRNP-E, Sm-E
Target Sequences: NM_003094 NP_003085.1 P62304

Filtered By: None
Target
SNRPE (16)
Reactivity
Human (16)
Mouse (11)
Rat (10)
Bat (8)
Bovine (8)
Chicken (8)
Chimpanzee (6)
Dog (8)
Gibbon (3)
Goat (4)
Guinea pig (8)
Hamster (8)
Monkey (8)
Pig (8)
Xenopus (4)
Zebrafish (4)
Application
IHC (4)
IHC-P (2)
WB (13)
ELISA (5)
ICC (1)
IF (5)
Host
rabbit (16)
Isotype
IgG (6)
Clonality
polyclonal pc (16)
Format
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (7)
Epitope
N-Terminus (4)
aa30-79 (4)
Publications
No (16)
Showing 1-16 of 16 results

SNRPE Antibody LS-C482456
Rabbit Polyclonal to Human SNRPE
Mouse, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Immunohistochemical analysis of Sm E staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Sm E staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Immunohistochemical analysis of Sm E staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Sm E staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.

SNRPE Antibody LS-C681411
Rabbit Polyclonal (IgG) to Human SNRPE
Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry Dilution at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of U251 cells diluted at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The Secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Immunohistochemistry Dilution at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of U251 cells diluted at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The Secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).

SNRPE Antibody (HRP) LS-C681415
Rabbit Polyclonal (IgG) to Human SNRPE
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg  $385.00

SNRPE Antibody (Biotin) LS-C681413
Rabbit Polyclonal (IgG) to Human SNRPE
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

SNRPE Antibody (FITC) LS-C681416
Rabbit Polyclonal (IgG) to Human SNRPE
Human
ELISA
FITC Conjugated
50µg  $285.00; 100µg  $385.00

SNRPE Antibody LS-C755261
Rabbit Polyclonal (IgG) to Human SNRPE
Human
ELISA IF IHC WB
Unconjugated
100µg  $355.00

SNRPE Antibody LS-C334087
Rabbit Polyclonal (IgG) to Human SNRPE
Mouse, Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded human kidney tissue.
Immunohistochemistry of paraffin-embedded human stomach cancer tissue.
Immunohistochemistry of paraffin-embedded human kidney tissue.
Immunohistochemistry of paraffin-embedded human stomach cancer tissue.

SNRPE Antibody LS-C341637
Rabbit Polyclonal to Human SNRPE
Mouse, Rat, Human
IF WB
Unconjugated
100µl 1mg/ml  $385.00

SNRPE Antibody (aa30-79) LS-C146244
Rabbit Polyclonal to Human SNRPE
Chicken, Bovine, Mouse, Goat, Dog, Guinea pig, Rat, Hamster, Pig, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
SNRPE antibody Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SNRPE antibody Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SNRPE Antibody (aa30-79, HRP) LS-C470662
Rabbit Polyclonal to Human SNRPE
Chicken, Bovine, Mouse, Goat, Dog, Guinea pig, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
SNRPE antibody Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SNRPE antibody Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SNRPE Antibody (aa30-79, Biotin) LS-C470660
Rabbit Polyclonal to Human SNRPE
Chicken, Bovine, Mouse, Goat, Dog, Guinea pig, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
SNRPE antibody Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SNRPE antibody Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SNRPE Antibody (aa30-79, FITC) LS-C470661
Rabbit Polyclonal to Human SNRPE
Chicken, Bovine, Mouse, Goat, Dog, Guinea pig, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
SNRPE antibody Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SNRPE antibody Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SNRPE Antibody (N-Terminus) LS-C146245
Rabbit Polyclonal to Human SNRPE
Xenopus, Chicken, Zebrafish, Pig, Bat, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Human, Monkey
WB
Unconjugated
50µg  $365.00
SNRPE antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SNRPE antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SNRPE Antibody (N-Terminus, HRP) LS-C470490
Rabbit Polyclonal to Human SNRPE
Xenopus, Chicken, Zebrafish, Bat, Pig, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
SNRPE antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SNRPE antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SNRPE Antibody (N-Terminus, Biotin) LS-C470663
Rabbit Polyclonal to Human SNRPE
Xenopus, Chicken, Zebrafish, Bat, Pig, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
SNRPE antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SNRPE antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SNRPE Antibody (N-Terminus, FITC) LS-C470664
Rabbit Polyclonal to Human SNRPE
Xenopus, Chicken, Zebrafish, Bat, Pig, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $385.00
SNRPE antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SNRPE antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-16 of 16 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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