LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us

SNCA / Alpha-Synuclein

synuclein, alpha (non A4 component of amyloid precursor)

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

Gene Name: synuclein, alpha (non A4 component of amyloid precursor)
Synonyms: SNCA, Alpha-synuclein, PARK4, PD1, Synuclein alpha-140, NACP, PARK1
Target Sequences: NM_000345 NP_000336.1 P37840

Publications (3)

1
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM. Science (New York, N.Y.). 2000 290:985-9. [PubMed:11062131]
2
Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications. Qing H, Wong W, McGeer EG, McGeer PL. Biochemical and biophysical research communications. 2009 387:149-52. (WB) [PubMed:19576176]
3
Determining nuclear localization of alpha-synuclein in mouse brains. Huang Z, Xu Z, Wu Y, Zhou Y. Neuroscience. 2011 199:318-32. [PubMed:22033456] [PMC:PMC3237852]

Filtered By: None
Type
Cell-Based (1)
Cell-Based Phosphorylation (2)
Competitive EIA (3)
Custom (8)
Sandwich (13)
Sandwich CLIA (2)
Target
SNCA / Alpha-Synuclein (29)
Reactivity
Human (10)
Mouse (10)
Rat (8)
Chicken (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
Sheep (1)
Sample Type
Adherent Cell Cultures (3)
Cell Culture Supernatants (1)
Cell Lysates (1)
Cerebrospinal Fluid (1)
Plasma (18)
Serum (18)
Tissue Homogenates (5)
Showing 1-25 of 29 results

Mouse SNCA / Alpha-Synuclein ELISA Kit (Sandwich ELISA) - LS-F23116
Sandwich
96-Well Microplate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Human SNCA / Alpha-Synuclein ELISA Kit (Sandwich ELISA) - LS-F12684
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $650.00
LSBio image for ELISA Kit

Mouse SNCA / Alpha-Synuclein ELISA Kit (Sandwich ELISA) - LS-F6284
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate  $650.00
LSBio image for ELISA Kit

Sheep SNCA / Alpha-Synuclein ELISA Kit (Custom ELISA) - LS-F48306
Custom
96-Well Strip Plate
Sheep
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
1plate  $730.00
LSBio image for ELISA Kit

Rabbit SNCA / Alpha-Synuclein ELISA Kit (Custom ELISA) - LS-F48307
Custom
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Porcine SNCA / Alpha-Synuclein ELISA Kit (Custom ELISA) - LS-F48305
Custom
96-Well Strip Plate
Porcine
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Monkey SNCA / Alpha-Synuclein ELISA Kit (Custom ELISA) - LS-F48304
Custom
96-Well Strip Plate
Monkey
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Chicken SNCA / Alpha-Synuclein ELISA Kit (Custom ELISA) - LS-F48303
Custom
96-Well Strip Plate
Chicken
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Rat SNCA / Alpha-Synuclein ELISA Kit (Custom ELISA) - LS-F16481
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Pig SNCA / Alpha-Synuclein ELISA Kit (Custom ELISA) - LS-F16482
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Bovine SNCA / Alpha-Synuclein ELISA Kit (Custom ELISA) - LS-F16484
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Mouse SNCA / Alpha-Synuclein ELISA Kit (Sandwich ELISA) - LS-F16483
Sandwich
96-Well Strip Plate
Mouse
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Human SNCA / Alpha-Synuclein ELISA Kit (Sandwich ELISA) - LS-F22954
Sandwich
96-Well Microplate
Human
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Mouse/Human/Rat Phospho-SNCA / Alpha-Synuclein (Tyr136) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1635
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1plate  $590.00
LSBio image for ELISA Kit

Mouse/Human/Rat Phospho-SNCA / Alpha-Synuclein (Tyr133) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1634
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1plate  $590.00
LSBio image for ELISA Kit

Human SNCA / Alpha-Synuclein ELISA Kit (Sandwich ELISA) - LS-F4486
Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cerebrospinal Fluid, Plasma, Serum
1plate  $630.00
LSBio image for ELISA Kit

Mouse/Human/Rat SNCA / Alpha-Synuclein ELISA Kit (Cell-Based ELISA) - LS-F2342
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1plate  $490.00
LSBio image for ELISA Kit

Rat SNCA / Alpha-Synuclein ELISA Kit (Sandwich ELISA) - LS-F9636
Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $690.00
LSBio image for ELISA Kit

Mouse SNCA / Alpha-Synuclein ELISA Kit (Competitive EIA) - LS-F28943
Competitive EIA
96-Well Strip Plate
Mouse
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit

Rat SNCA / Alpha-Synuclein ELISA Kit (Competitive EIA) - LS-F28890
Competitive EIA
96-Well Strip Plate
Rat
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit

Human SNCA / Alpha-Synuclein ELISA Kit (Sandwich ELISA) - LS-F28833
Sandwich
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit

Human SNCA / Alpha-Synuclein ELISA Kit (CLIA) - LS-F29669
Sandwich CLIA
12 x 8-Well Microstrips
Human
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Human SNCA / Alpha-Synuclein ELISA Kit (Sandwich ELISA) - LS-F27231
Sandwich
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit

Mouse SNCA / Alpha-Synuclein ELISA Kit (Competitive EIA) - LS-F28600
Competitive EIA
96-Well Strip Plate
Mouse
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit

Rat SNCA / Alpha-Synuclein ELISA Kit (Sandwich ELISA) - LS-F23251
Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit
Showing 1-25 of 29 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2019 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy