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SNAREs, Soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Probably involved in multiple membrane trafficking steps.
Gene Name: | synaptosomal-associated protein, 29kDa |
Synonyms: | SNAP29, CEDNIK, SNAP-29 |
Target Sequences: | NM_004782 NP_004773.1 O95721 |
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