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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SMPD1 / Acid Sphingomyelinase

sphingomyelin phosphodiesterase 1, acid lysosomal

Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Isoform 2 and isoform 3 have lost catalytic activity.

Gene Name: sphingomyelin phosphodiesterase 1, acid lysosomal
Family/Subfamily: Phosphodiesterase - Other , not assigned-Phosphodiesterase - Other
Synonyms: SMPD1, Acid sphingomyelinase, ASM, NPD, ASMASE
Target Sequences: NM_000543 NP_000534.3 P17405

Filtered by: None
Target
SMPD1 / Acid Sphingomyelinase (33)
Reactivity
Human (33)
Mouse (15)
Rat (6)
Bat (1)
Bovine (2)
Dog (1)
Horse (1)
Monkey (1)
Pig (1)
Rabbit (1)
Sheep (2)
Application
IHC (14)
IHC-P (5)
WB (32)
Flo (8)
ELISA (12)
IF (2)
IP (1)
Neut (1)
Host
rabbit (28)
mouse (4)
goat (1)
Isotype
IgG (11)
IgG1 (2)
IgG2a (1)
IgG2a,k (1)
Clonality
monoclonal mc (4)
polyclonal pc (29)
Clone
10C5 (1)
3H7 (1)
4H2 (1)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (17)
Epitope
aa319-579 (8)
aa391-419 (8)
aa79-128 (4)
aa62-341 (2)
Internal (1)
aa396-445 (1)
Publications
No (33)
Showing 1-25 of 33 results

IHC-plus™ SMPD1 / Acid Sphingomyelinase Antibody (aa391-419) LS-B10421
Rabbit Polyclonal to Human SMPD1 / Acid Sphingomyelinase
Human
Flo, IHC, IHC-P, WB
Unconjugated
200µl  $425.00
Anti-SMPD1 / Acid Sphingomyelinase antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-SMPD1 / Acid Sphingomyelinase antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

SMPD1 / Acid Sphingomyelinase Antibody LS-C334919
Rabbit Polyclonal (IgG) to Human SMPD1 / Acid Sphingomyelinase
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded rat ovary tissue.
Immunohistochemistry of paraffin-embedded rat spleen tissue.

SMPD1 / Acid Sphingomyelinase Antibody LS-C412564
Rabbit Polyclonal to Human SMPD1 / Acid Sphingomyelinase
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100µl  $385.00

SMPD1 / Acid Sphingomyelinase Antibody LS-C144184
Mouse Monoclonal (IgG2a) to Human SMPD1 / Acid Sphingomyelinase
Human
ELISA, IP, Neut
Unconjugated
100µg  $650.00

SMPD1 / Acid Sphingomyelinase Antibody (aa62-341, clone 10C5) LS-C339172
Mouse Monoclonal [clone 10C5] (IgG1) to Human SMPD1 / Acid Sphingomyelinase
Human
WB
Unconjugated
100µl 1mg/ml  $345.00
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SMPD1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SMPD1.

SMPD1 / Acid Sphingomyelinase Antibody (aa79-128) LS-C205675
Rabbit Polyclonal to Human SMPD1 / Acid Sphingomyelinase
Human
WB
Unconjugated
100µl 0.5mg/ml  $365.00
SMPD1 / Acid Sphingomyelinase antibody Western Blot of THP-1. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ SMPD1 / Acid Sphingomyelinase Antibody (aa396-445) LS-B9729
Rabbit Polyclonal (IgG) to Human SMPD1 / Acid Sphingomyelinase
Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl  $485.00
Anti-SMPD1 / Acid Sphingomyelinase antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Lane: Fetal Heart Lysate

SMPD1 / Acid Sphingomyelinase Antibody (aa391-419) LS-C330162
Rabbit Polyclonal (IgG) to Human SMPD1 / Acid Sphingomyelinase
Human
ELISA, Flo, IHC, WB
Unconjugated
200µl  $590.00

SMPD1 / Acid Sphingomyelinase Antibody (aa391-419, Biotin) LS-C269712
Rabbit Polyclonal (IgG) to Human SMPD1 / Acid Sphingomyelinase
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl  $740.00

SMPD1 / Acid Sphingomyelinase Antibody (aa391-419, FITC) LS-C269713
Rabbit Polyclonal (IgG) to Human SMPD1 / Acid Sphingomyelinase
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl  $740.00

SMPD1 / Acid Sphingomyelinase Antibody (aa391-419, APC) LS-C269711
Rabbit Polyclonal (IgG) to Human SMPD1 / Acid Sphingomyelinase
Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl  $740.00

SMPD1 / Acid Sphingomyelinase Antibody (aa391-419, PE) LS-C269714
Rabbit Polyclonal (IgG) to Human SMPD1 / Acid Sphingomyelinase
Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl  $740.00

SMPD1 / Acid Sphingomyelinase Antibody (aa391-419, AP) LS-C269710
Rabbit Polyclonal (IgG) to Human SMPD1 / Acid Sphingomyelinase
Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl  $740.00

SMPD1 / Acid Sphingomyelinase Antibody (aa391-419, Azide-free, HRP) LS-C269715
Rabbit Polyclonal (IgG) to Human SMPD1 / Acid Sphingomyelinase
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

IHC-plus™ SMPD1 / Acid Sphingomyelinase Antibody LS-B14228
Rabbit Polyclonal to Human SMPD1 / Acid Sphingomyelinase
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl  $425.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ SMPD1 / Acid Sphingomyelinase Antibody (Internal) LS-B14540
Rabbit Polyclonal to Human SMPD1 / Acid Sphingomyelinase
Mouse, Sheep, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Human Colon, Submucosal Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

SMPD1 / Acid Sphingomyelinase Antibody (aa62-341, clone 3H7) LS-C338823
Mouse Monoclonal [clone 3H7] (IgG1) to Human SMPD1 / Acid Sphingomyelinase
Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Human Ovary tissue using anti-SMPD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Human lymph node tissue using anti-SMPD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

SMPD1 / Acid Sphingomyelinase Antibody (clone 4H2) LS-C198226
Mouse Monoclonal [clone 4H2] (IgG2a,k) to Human SMPD1 / Acid Sphingomyelinase
Human
ELISA, WB
Unconjugated
100µg  $355.00
Western Blot analysis of SMPD1 expression in transfected 293T cell line by SMPD1 monoclonal antibody (M01), clone 4H2.Lane 1: SMPD1 transfected lysate(39.6 KDa).Lane 2: Non-transfected lysate.

SMPD1 / Acid Sphingomyelinase Antibody LS-C752878
Rabbit Polyclonal (IgG) to Human SMPD1 / Acid Sphingomyelinase
Human
ELISA, WB
Unconjugated
100µg  $355.00

SMPD1 / Acid Sphingomyelinase Antibody LS-C26834
Rabbit Polyclonal to Human SMPD1 / Acid Sphingomyelinase
Human
ELISA, WB
Unconjugated
100µg  $445.00
Western blot of acid sphingomyelinase antibody on normal human brain lysate (7 ug/lane). Antibody used at 1 ug/ml (1) and 0.5 ug/ml (2) and detected using mouse anti-rabbit antibody at 1:75k dilution and visualized using Pierce West Femto substrate.

SMPD1 / Acid Sphingomyelinase Antibody LS-C125890
Goat Polyclonal (IgG) to Human SMPD1 / Acid Sphingomyelinase
Mouse, Human
ELISA, WB
Unconjugated
100µg  $770.00

SMPD1 / Acid Sphingomyelinase Antibody (aa319-579) LS-C292595
Rabbit Polyclonal to Human SMPD1 / Acid Sphingomyelinase
Mouse, Human
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $495.00
Western blot of recombinant SMPD1 / Acid Sphingomyelinase.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Mouse Brain Tissue.

SMPD1 / Acid Sphingomyelinase Antibody (aa319-579, FITC) LS-C692324
Rabbit Polyclonal to Human SMPD1 / Acid Sphingomyelinase
Mouse, Human
WB
FITC Conjugated
100µl 0.5mg/ml  $275.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $590.00
Western blot of recombinant SMPD1 / Acid Sphingomyelinase.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Mouse Brain Tissue.

SMPD1 / Acid Sphingomyelinase Antibody (aa319-579, APC) LS-C716764
Rabbit Polyclonal to Human SMPD1 / Acid Sphingomyelinase
Mouse, Human
WB
APC Conjugated
100µl 0.1mg/ml  $265.00; 200µl 0.1mg/ml  $305.00; 1ml 0.1mg/ml  $560.00
Western blot of recombinant SMPD1 / Acid Sphingomyelinase.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Mouse Brain Tissue.

SMPD1 / Acid Sphingomyelinase Antibody LS-C314059
Rabbit Polyclonal to Human SMPD1 / Acid Sphingomyelinase
Mouse, Rat, Human
WB
Unconjugated
100µl  $385.00
Showing 1-25 of 33 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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