SMC6

structural maintenance of chromosomes 6

Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

SMC6 (6)

Publications

No (6)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

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SMC6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125847

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

126.1 kDa

Price:

100 µg/$710

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Human SMC6 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72238

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

126.1 kDa

Price:

20 µg/$1,107

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Human SMC6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91784

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

126.1 kDa

Price:

20 µg/$150

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Human SMC6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91783

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

126.1 kDa

Price:

20 µg/$215

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Human SMC6 Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G63184

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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SMC6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101901

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

126.1 kDa

Price:

100 µg/$494

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