SLIT2

slit homolog 2 (Drosophila)

Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.

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Products

ELISA Kits (25)

Type

Competitive EIA (2)

Custom (2)

Sandwich (19)

Sandwich CLIA (2)

Target

SLIT2 (25)

Reactivity

Human (6)

Mouse (8)

Rat (4)

Chicken (1)

Guinea pig (1)

Monkey (1)

Pig (2)

Rabbit (1)

Sheep (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (5)

96-Well Strip Plate (18)

Publications

No (25)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (2)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (16)

Serum (17)

Tissue Homogenates (8)

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Human SLIT2 (Sandwich ELISA) ELISA Kit - LS-F21017

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$771

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Human SLIT2 (Sandwich ELISA) ELISA Kit - LS-F4840

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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Mouse SLIT2 (Sandwich ELISA) ELISA Kit - LS-F4841

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$782

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Human SLIT2 (Sandwich ELISA) ELISA Kit - LS-F12612

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse SLIT2 (Sandwich ELISA) ELISA Kit - LS-F57327

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$795

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Rat SLIT2 (Sandwich ELISA) ELISA Kit - LS-F6346

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$818

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Chicken SLIT2 (Sandwich ELISA) ELISA Kit - LS-F48067

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Monkey SLIT2 (Sandwich ELISA) ELISA Kit - LS-F48068

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Guinea pig SLIT2 (Sandwich ELISA) ELISA Kit - LS-F48069

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit SLIT2 (Sandwich ELISA) ELISA Kit - LS-F48070

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Sheep SLIT2 (Sandwich ELISA) ELISA Kit - LS-F48071

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$760

Select

Rat SLIT2 (Custom ELISA) ELISA Kit - LS-F15002

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Mouse SLIT2 (Custom ELISA) ELISA Kit - LS-F15003

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human SLIT2 (CLIA) ELISA Kit - LS-F29644

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Rat SLIT2 (Sandwich ELISA) ELISA Kit - LS-F21605

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Mouse SLIT2 (Sandwich ELISA) ELISA Kit - LS-F22248

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Mouse SLIT2 (Competitive EIA) ELISA Kit - LS-F28597

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Mouse SLIT2 (CLIA) ELISA Kit - LS-F30869

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

62.5 - 4000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Pig SLIT2 (Sandwich ELISA) ELISA Kit - LS-F22391

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Pig

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Human SLIT2 (Competitive EIA) ELISA Kit - LS-F27809

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Rat SLIT2 (Sandwich ELISA) ELISA Kit - LS-F34059

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human SLIT2 (Sandwich ELISA) ELISA Kit - LS-F34060

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Pig SLIT2 (Sandwich ELISA) ELISA Kit - LS-F34061

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse SLIT2 (Sandwich ELISA) ELISA Kit - LS-F34067

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse SLIT2 (Sandwich ELISA) ELISA Kit - LS-F53402

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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