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Mediates the Na+-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a signifiant role in regulating T4 flux into and out of the brain.
Gene Name: | solute carrier organic anion transporter family, member 1C1 |
Family/Subfamily: | Transporter , Organic anion transporter |
Synonyms: | SLCO1C1, Oatp1, Organic anion transporter F, Thyroxine transporter, OAT-RP-5, OATP14, SLC21A14, OATP-14, OATP-F, OATP1C1, OATPF, OATPRP5 |
Target Sequences: | NM_017435 NP_059131.1 Q9NYB5 |
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