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SLC9A8 / NHE8

solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8

Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.

Gene Name: solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
Family/Subfamily: Transporter , Monovalent cation:proton antiporter-1
Synonyms: SLC9A8, KIAA0939, Na(+)/H(+) exchanger 8, NHE8, NHE-8, Sodium/hydrogen exchanger 8
Target Sequences: AB023156 BAA76783.2 Q9Y2E8

Publications (4)

1
Immunolocalization of NHE8 in rat kidney. Goyal S, Mentone S, Aronson PS. American journal of physiology. Renal physiology. 2005 288:F530-8. (ICC, WB) [PubMed:15522984]
2
Characterization of Na+/H+ exchanger NHE8 in cultured renal epithelial cells. Zhang J, Bobulescu IA, Goyal S, Aronson PS, Baum MG, Moe OW. American journal of physiology. Renal physiology. 2007 293:F761-6. [PubMed:17581925] [PMC:PMC2861566]
3
Effect of metabolic acidosis on neonatal proximal tubule acidification. Twombley K, Gattineni J, Bobulescu IA, Dwarakanath V, Baum M. American journal of physiology. Regulatory, integrative and comparative physiology. 2010 299:R1360-8. [PubMed:20720175] [PMC:PMC2980451]
4
Nucleotide sequence of the Na+/H+ exchanger-8 in patients with congenital sodium diarrhea. Baum M, Martin MG, Booth IW, Holmberg C, Twombley K, Zhang Q, Gattineni J, Moe O. Journal of pediatric gastroenterology and nutrition. 2011 53:474-7. [PubMed:21666503]
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☰ Filters
Antibodies (18)
Proteins (2)
Over-Expression Lysate (2)
Primary (18)
SLC9A8 / NHE8 (20)
Human (18)
Mouse (10)
Rat (10)
Chicken (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (4)
Rabbit (3)
Xenopus (3)
IHC (4)
IHC-P (1)
WB (18)
ELISA (8)
ICC (2)
IF (7)
Peptide-ELISA (3)
rabbit (12)
mouse (5)
rabbit-new zealand white (1)
IgG (16)
monoclonal mc (5)
polyclonal pc (13)
7A11 (5)
Biotin Conjugated (2)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (11)
C-Terminus (10)
420-500 aa, C-terminal (1)
aa440-489 (1)
aa450-500 (1)
aa451-500 (1)
No (20)
Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
SLC9A8 / NHE8 Antibody - SLC9A8 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
SLC9A8 / NHE8 Antibody - SLC9A8 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Xenopus, Chicken, Rat, Rabbit, Mouse, Dog, Guinea pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
SLC9A8 / NHE8 Antibody - SLC9A8 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Xenopus, Chicken, Rat, Rabbit, Mouse, Dog, Guinea pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
SLC9A8 / NHE8 Antibody - SLC9A8 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Xenopus, Chicken, Rat, Rabbit, Mouse, Dog, Guinea pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
SLC9A8 / NHE8 Antibody - Western blot of NHE-8 antibody
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal (420-500 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, ICC, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SLC9A8 / NHE8 Antibody - Immunohistochemical analysis of NHE8 staining in human skeletal muscle formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
SLC9A8 / NHE8 Antibody - Detection of NHE8 (7A11) in HeLa whole cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A8 / NHE8 Mouse anti-Human Monoclonal (C-Terminus) (7A11) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
0.1 ml/$386
SLC9A8 / NHE8 Antibody - Detection of NHE8 (7A11) in HeLa whole cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A8 / NHE8 Mouse anti-Human Monoclonal (C-Terminus) (Biotin) (7A11) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Biotin Conjugated
0.1 ml/$416
SLC9A8 / NHE8 Antibody - Detection of NHE8 (7A11) in HeLa whole cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A8 / NHE8 Mouse anti-Human Monoclonal (C-Terminus) (DY550) (7A11) Antibody
Human
ELISA, IF, WB
DY550 Conjugated
0.1 ml/$416
SLC9A8 / NHE8 Antibody - Detection of NHE8 (7A11) in HeLa whole cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A8 / NHE8 Mouse anti-Human Monoclonal (C-Terminus) (DY650) (7A11) Antibody
Human
ELISA, IF, WB
DY650 Conjugated
0.1 ml/$416
SLC9A8 / NHE8 Antibody - Detection of NHE8 (7A11) in HeLa whole cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A8 / NHE8 Mouse anti-Human Monoclonal (C-Terminus) (DY488) (7A11) Antibody
Human
ELISA, IF, WB
DY488 Conjugated
0.1 ml/$416
SLC9A8 / NHE8 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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SLC9A8 / NHE8 Rabbit-New Zealand White anti-Human Polyclonal (aa450-500) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
SLC9A8 / NHE8 Antibody - Western blot analysis of lysates from Jurkat cells, using SLC9A8 Antibody. The lane on the right is blocked with the synthesized peptide.
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal (aa451-500) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SLC9A8 / NHE8 Antibody - Western blot analysis of the lysates from HeLa cells using SLC9A8 antibody.
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal (aa440-489) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SLC9A8 / NHE8 Antibody - Western blot analysis of extracts of 293T cells, using SLC9A8 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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SLC9A8 / NHE8 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
SLC9A8 / NHE8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
65.2 kDa
100 µg/$494
SLC9A8 / NHE8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
65.2 kDa
20 µg/$150
Viewing 1-20 of 20 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).