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SLC5A2 / SGLT2

solute carrier family 5 (sodium/glucose cotransporter), member 2

Sodium-dependent glucose transporter. Has a Na+ to glucose coupling ratio of 1:1.Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na+/glucose cotransporter arranged in series along kidney proximal tubules.

Gene Name: solute carrier family 5 (sodium/glucose cotransporter), member 2
Family/Subfamily: Transporter , Solute:sodium symporter
Synonyms: SLC5A2, Na(+)/glucose cotransporter 2, SGLT2, Sodium-glucose transporter 2, Sodium/glucose cotransporter 2
Target Sequences: NM_003041 NP_003032.1 P31639

Publications (1)

1
No direct effect of SGLT2 activity on glucagon secretion. Rune E Kuhre, Seyed M Ghiasi, Alice E Adriaenssens, Nicolai J Wewer Albrechtsen, Daniel B Andersen, Alexander Aivazidis, Lihua Chen, Thomas Mandrup-Poulsen, Cathrine Ørskov, Fiona M Gribble, Frank Reimann, Nils Wierup, Björn Tyrberg, Jens J Holst. Diabetologia. 2019 Jun;62:1011-1023. [Full Text Article] [PubMed:30903205] [PMC:PMC7212061] Related Antibodies: LS-A2810.

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
SLC5A2 / SGLT2 (6)
No (6)
10His, N-terminus + Myc, C-terminus (1)
10His-SUMO, N-terminus + Myc, C-terminus (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (3)
SLC5A2 / SGLT2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SLC5A2 / SGLT2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
72.7 kDa
100 µg/$710
SLC5A2 / SGLT2 Protein - 12.5% SDS-PAGE of human SLC5A2 stained with Coomassie Blue
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Wheat Germ Extract
GST
99.3 kDa
2 µg/$439
SLC5A2 / SGLT2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His-SUMO, N-terminus + Myc, C-terminus
100 µg/$1,128; 20 µg/$721
SLC5A2 / SGLT2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
1 mg/$1,486; 100 µg/$451; 20 µg/$339
SLC5A2 / SGLT2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
72.7 kDa
20 µg/$215
Viewing 1-6 of 6 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).