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SLC40A1 / Ferroportin-1

solute carrier family 40 (iron-regulated transporter), member 1

May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).

Gene Name: solute carrier family 40 (iron-regulated transporter), member 1
Family/Subfamily: Transporter , Natural resistance-associated macrophage protein (NRAMP)
Synonyms: SLC40A1, Ferroportin, FPN1, Iron-regulated transporter 1, MST079, MSTP079, IREG1, Iron regulated gene 1, SLC11A3, MTP1, Ferroportin-1, HFE4
Target Sequences: NM_014585 NP_055400.1 Q9NP59

Publications (8)

1
Intestinal ferritin H is required for an accurate control of iron absorption. Vanoaica L, Darshan D, Richman L, Schmann K, Khn LC. Cell metabolism. 2010 12:273-82. [PubMed:20816093]
2
mTOR regulates cellular iron homeostasis through tristetraprolin. Bayeva M, Khechaduri A, Puig S, Chang HC, Patial S, Blackshear PJ, Ardehali H. Cell metabolism. 2012 16:645-57. (WB; Mouse) [PubMed:23102618] [PMC:PMC3594686]
3
Inducible and reversible phenotypes in a novel mouse model of Friedreich's Ataxia. Chandran V, Gao K, Swarup V, Versano R, Dong H, Jordan MC, Geschwind DH,. eLife. 2017 6: (WB; Human) [Full Text Article] [PubMed:29257745] Related Antibodies: LS-B1836.
4
Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction. Ross SL, Biswas K, Rottman J, Allen JR, Long J, Miranda LP, Winters A, Arvedson TL. Frontiers in pharmacology. 2017 8:838. (WB; Human) [Full Text Article] [PubMed:29209212] Related Antibodies: LS-B1836.
5
Increased Duodenal Iron Absorption through Upregulation of Ferroportin 1 due to the Decrement in Serum Hepcidin in Patients with Chronic Hepatitis C. Sato M, Miyanishi K, Tanaka S, Sakurada A, Sakamoto H, Kawano Y, Takada K, Kobune M, Kato J. Canadian journal of gastroenterology & hepatology. 2018 August;2018:2154361. [Full Text Article] [PubMed:30186818] [PMC:PMC6112088] Related Antibodies: LS-B1836.
6
Extracellular Vesicles Reveal Abnormalities In Neuronal Iron Metabolism In Restless Legs Syndrome. Sahil Chawla, Seema Gulyani, Richard P Allen, Christopher J Earley, Xu Li, Peter Van Zijl, Dimitrios Kapogiannis. Sleep. 2019 March; [Full Text Article] [PubMed:30895312] [PMC:PMC6612672]
7
Unbalance in Iron Metabolism in Childhood Leukemia Converges with Treatment Intensity: Biochemical and Clinical Analysis. Monika Lecka, Artur Slomka, Katarzyna Albrecht, Ewa Zekanowska, Michal Romiszewski, Jan Styczynski. Cancers. 2021 June;13:3029. [Full Text Article] [PubMed:34204310] [PMC:PMC8233795]
8
Neonatal iron overload and tissue siderosis due to gestational alloimmune liver disease. Bonilla S, Prozialeck JD, Malladi P, Pan X, Yu S, Melin-Aldana H, Whitington PF. Journal of hepatology. 2014 Jun;56:1351-5. [Full Text Article] [PubMed:22322235] Related Antibodies: LS-B1836.
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Antibodies (53)
Primary (53)
SLC40A1 / Ferroportin-1 (53)
Human (50)
Mouse (11)
Rat (10)
Bovine (1)
Pig (10)
IHC (9)
IHC-P (9)
WB (44)
Flo (5)
ELISA (9)
ICC (5)
IF (1)
Peptide-ELISA (2)
rabbit (28)
mouse (24)
goat (1)
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IHCPlus (1)
PathPlus Cancer (2)
IgG (13)
IgG2b,k (24)
monoclonal mc (24)
polyclonal pc (29)
APC (4)
APC Conjugated (4)
Biotin Conjugated (6)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (18)
aa127-321 (8)
aa250-300 (4)
C-Terminus (2)
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Yes (1)
SLC40A1 / Ferroportin-1 Antibody - Anti-SLC40A1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
SLC40A1 / Ferroportin-1 Antibody - Anti-SLC40A1 / Ferroportin-1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Cancer
SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
SLC40A1 / Ferroportin-1 Antibody - Anti-SLC40A1 / Ferroportin-1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal (aa250-300) (Biotin) Antibody
Mouse, Human
Flo, ICC, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
SLC40A1 / Ferroportin-1 Antibody - Anti-SLC40A1 / Ferroportin-1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal (aa250-300) (DY650) Antibody
Mouse, Bovine, Pig, Human
Flo, ICC, IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
SLC40A1 / Ferroportin-1 Antibody - Anti-SLC40A1 / Ferroportin-1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal (aa250-300) (DY488) Antibody
Mouse, Human
Flo, ICC, IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
SLC40A1 / Ferroportin-1 Antibody - Anti-SLC40A1 / Ferroportin-1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal (aa250-300) (DY550) Antibody
Mouse, Human
Flo, ICC, IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
SLC40A1 / Ferroportin-1 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
Flo, ICC, IHC-P, WB
Unconjugated
50 µl/$447
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SLC40A1 / Ferroportin-1 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µl/$801
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SLC40A1 / Ferroportin-1 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µl/$832
SLC40A1 / Ferroportin-1 Antibody
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SLC40A1 / Ferroportin-1 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Pig, Human
WB
Unconjugated
100 µl/$312; 200 µl/$355; 500 µl/$500; 1 ml/$573; 2 ml/$780; 5 ml/$1,268
SLC40A1 / Ferroportin-1 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
SLC40A1 / Ferroportin-1 Antibody
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SLC40A1 / Ferroportin-1 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$312; 200 µl/$355; 500 µl/$500; 1 ml/$573; 2 ml/$780; 5 ml/$1,268
SLC40A1 / Ferroportin-1 Antibody
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SLC40A1 / Ferroportin-1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$342; 200 µl/$399; 500 µl/$587; 1 ml/$725; 2 ml/$962; 5 ml/$1,648
SLC40A1 / Ferroportin-1 Antibody
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SLC40A1 / Ferroportin-1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$322; 200 µl/$370; 500 µl/$529; 1 ml/$614; 2 ml/$846; 5 ml/$1,395
SLC40A1 / Ferroportin-1 Antibody
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SLC40A1 / Ferroportin-1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$352; 200 µl/$413; 500 µl/$625; 1 ml/$780; 2 ml/$1,018; 5 ml/$1,775
SLC40A1 / Ferroportin-1 Antibody
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SLC40A1 / Ferroportin-1 Mouse anti-Human Monoclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$413; 200 µl/$500; 500 µl/$872; 1 ml/$1,034; 2 ml/$1,352; 5 ml/$2,535
SLC40A1 / Ferroportin-1 Antibody - Western blot analysis of extracts of mouse small intestine, using SLC40A1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
SLC40A1 / Ferroportin-1 Antibody - Immunofluorescent analysis of HepG2 cells using SLC40A1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
SLC40A1 / Ferroportin-1 Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using SLC40A1 Polyclonal Antibody at dilution of 1:90(×200)
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SLC40A1 / Ferroportin-1 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer tissue  using SLC40A1 Polyclonal Antibody at dilution of 1:65(×200)
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC
Unconjugated
20 µl/$275; 100 µl/$389
SLC40A1 / Ferroportin-1 Antibody - Goat Anti-SLC40A1 (aa245-259) Antibody (1µg/ml) staining of Breast Cancer lysate (35µg protein in RIPA buffer). Detected by chemiluminescencence.
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SLC40A1 / Ferroportin-1 Goat anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
SLC40A1 / Ferroportin-1 Antibody
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SLC40A1 / Ferroportin-1 Mouse anti-Human Monoclonal Antibody
Pig, Human
WB
Unconjugated
100 µl/$312; 200 µl/$355; 500 µl/$500; 1 ml/$573; 2 ml/$780; 5 ml/$1,268
SLC40A1 / Ferroportin-1 Antibody - Western blot of recombinant SLC40A1 / Ferroportin-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC40A1 / Ferroportin-1 Rabbit anti-Human Polyclonal (aa127-321) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).