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Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.
Gene Name: | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
Synonyms: | SLC35D2, Fringe connection, HFRC1, Hfrc, SQV7-like protein, SQV7L, UGTrel8 |
Target Sequences: | IPI00029935.3 Q76EJ3 |
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