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SLC25A19

solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19

SLC25A19 is a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

Gene Name: solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
Family/Subfamily: Transporter , Mitochondrial carrier
Synonyms: SLC25A19, DNC, THMD4, MCPHA, TPC, Microcephaly, Amish, THMD3
Target Sequences: NM_021734 NP_068380.3 Q9HC21

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
SLC25A19 (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
SLC25A19 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35.3 kDa
100 µg/$494
SLC25A19 Protein - 12.5% SDS-PAGE of human SLC25A19 stained with Coomassie Blue
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Wheat Germ Extract
GST
60.94 kDa
2 µg/$439
SLC25A19 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
35.3 kDa
20 µg/$150
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).