Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SLC22a3 (Solute carrier family 22, member 3), also known as EMT (Extraneuronal monoamine transporter) or OCT3 (Organic cation transporter 3), possesses properties of a polyspecific organic cation transporter. It is critical for the elimination of endogenous amines, drugs, and environmental toxins. Also, SLC22a3 may play a role in the disposition of cationic neurotoxins and neurotransmitters in the brain. The activity of this protein can be inhibited by steroid compounds, especially by beta-estradiol. Caution: The synonym EMT also is used as an abbreviation for Interleukin 2 Tyrosine Kinase.
|Gene Name:||solute carrier family 22 (organic cation transporter), member 3|
|Family/Subfamily:||Transporter , Organic cation transporter|
|Synonyms:||SLC22A3, EMTH, OCT3, Organic cation transporter 3, EMT|
|Target Sequences:||NM_021977 NP_068812.1 O75751|
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